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CD41 Antibody – Human Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS488496

Recombinant monoclonal antibody to CD41. Manufactured using our Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 7E3 (Abciximab). More details

$635 / 0.2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD41, Monoclonal Antibody
Full Product Name
Anti-CD41 [7E3 (Abciximab)], Human IgG1, Kappa
Product Gene Name
Product Synonym Names
Integrin alpha-IIb, Integrin alpha-2b, ITGA2B, platelet glycoprotein IIb of IIb/IIIa complex
Clonality
Monoclonal
Isotype
Human IgG1, Kappa
Clone Number
7E3
Host
Human
Species Reactivity
Human
Form/Format
PBS with 0.02% Proclin 300
Purity/Purification
Protein A affinity purified
Concentration
1mg/ml (lot specific)
Specificity
Recognises human CD41.
Preparation and Storage
Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.
Molecular Weight
1039
Chromosome Location
Chromosome: 17; NC_000017.10 (42449550..42466873, complement). Location: 17q21.32
OMIM
273800
3D Structure
ModBase 3D Structure for P08514
Animal-free Manufacturing Platform
The recombinant antibody is manufactured using a recombinant, mammalian HEK293-based expression platform. The manufacturing platform is animal-free and animal component-free.
Antibody Type
Recombinant Antibody
Immunogen
CD41 is the integrin alpha chain 2b forming a fibrinogen receptor in heterodimeric complex with beta 3.
Chimeric Use Statement
This is a reformatted human IgG1 antibody based on the therapeutic Fab fragment. NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.

Product Categories/Family for anti-CD41 antibody

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CD41 antibody
Blocking (BL), Flow Cytometry (FC/FACS)

Flow Cytometry (FC/FACS) of anti-CD41 antibody

Flow-cytometry using the anti-CD41 research biosimilar antibody Abciximab (7E3) Human lymphocytes were stained with an isotype control or the rabbit-chimeric version of Abciximab at a concentration of 1ug/ml for 30 mins at RT. After washing, bound antibody was detected using a AF488 conjugated donkey anti-rabbit antibody and cells analysed on a FACSCanto flow-cytometer.
Human Anti-CD41 Monoclonal Antibody – Cat# MBS488496

Product References and Citations for anti-CD41 antibody

N Engl J Med.

Other Notes

Small volumes of anti-CD41 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD41 purchase

MBS488496 is an antibody targeting CD41. Also known as Anti-CD41 [7E3 (Abciximab)], Human IgG1, Kappa. Reactive in Human. Host: Human.

Additional Details

NCBI/Uniprot data below describe general gene information for CD41. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
integrin alpha-IIb preproprotein
NCBI Official Synonym Full Names
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
NCBI Official Symbol
ITGA2B
NCBI Official Synonym Symbols
GT; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2; BDPLT16
UniProt Protein Name
Integrin alpha-IIb
UniProt Synonym Protein Names
GPalpha IIb; GPIIb; Platelet membrane glycoprotein IIb
Protein Family
UniProt Gene Name
ITGA2B
UniProt Synonym Gene Names
GP2B; ITGAB; GPIIb
UniProt Entry Name
ITA2B_HUMAN
NCBI Protein Information
integrin alpha-IIb; GPalpha IIb; platelet-specific antigen BAK; platelet membrane glycoprotein IIb; platelet fibrinogen receptor, alpha subunit

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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