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YRS Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS490302

Tyrosyl-tRNA synthetase (YRS) catalyzes the ligation of tyrosine with tyrosyl-tRNA. YRS is secreted and induced vascular angiogenesis. More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
YRS (Tyrosyl-tRNA Synthetase), Polyclonal Antibody
Full Product Name
YRS (Tyrosyl-tRNA Synthetase)
Product Gene Name
anti-YRS antibody
Product Synonym Names
Tyrosyl-tRNA Synthetase pAb; tyrRS; YARS; YTS
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Other species are not tested.
Form/Format
Serum containing 0.05% sodium azide for preservative.
Specificity
This antibody reacts specifically with 51kDa tyrosyl tRNA synthetase protein.
Preparation and Storage
Store at 4 degree C or -20 degree C.
3D Structure
ModBase 3D Structure for P95982
Immunogen
Native full length human recombinant YRS.
Applications Tested/Suitable for anti-YRS antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-YRS antibody
WB: 1:10000

Western Blot (WB) of anti-YRS antibody

Rabbit Anti-YRS Polyclonal Antibody – Cat# MBS490302

Immunofluorescence (IF) of anti-YRS antibody

Rabbit Anti-YRS Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS490302

Product References and Citations for anti-YRS antibody

1. The tyrosyl-tRNA synthetase like gene located in the tyramine biosynthesis cluster of Enterococcus durans is transcriptionally regulated by tyrosine concentration and extracellular pH. Daniel M Linares et al., BMC Microbiology, 12:23, 2012. 2. Comparative structural dynamics of Tyrosyl-tRNA synthetase complexed with different substrates explored by molecular dynamics. Tong Li et al., Eur Biophys J, Vol.38, 25-35, 2008. 3. An engineered Escherichia coli tyrosyl-tRNA synthetase for site-specific incorporation of an unnatural amino acid into proteins in eukaryotic translation and its application in a wheat germ cell-free system. Daisuke Kiga et al., PNAS, Vol.99(15), 9715-9723, 2002. 4. Structure-based design of mutant Methanococcus jannaschii tyrosyl-tRNA synthetase for incorporation of O-methyl-L-tyrosine. Deqiang Zhang et al., PNAS, Vol.99(10), 6579-6584, 2002. 5. The Anticodon-binding Domain of Tyrosyl-tRNA Synthetase: State of Folding and Origin of the Crystallographic Disorder. Vale´rie Guez et al., Biochemistry, Vol.39, 1739-1747, 2000.

Other Notes

Small volumes of anti-YRS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for YRS purchase

MBS490302 is an antibody targeting YRS. Also known as YRS (Tyrosyl-tRNA Synthetase). Reactive in Human, Mouse
Other species are not tested.. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for YRS. It may not necessarily be applicable to this product.

NCBI GI #
1707816
NCBI Accession #
CAA69524.1
UniProt Primary Accession #
P95982
NCBI Official Full Name
tyrosyl tRNA synthetase
UniProt Protein Name
Tyrosine--tRNA ligase
UniProt Synonym Protein Names
Tyrosyl-tRNA synthetase
UniProt Gene Name
tyrS
UniProt Synonym Gene Names
TyrRS

UniProt Comments for YRS

Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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