Tyrosine Hydroxylase (TH) ELISA Kit for Monkey

Name: Monkey TH ELISA Kit; Tyrosine Hydroxylase; MyBioSource
Brand: MyBioSource
SKU: MBS004911
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS004911

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only. This kit is intended to be used for determination the level of TH (hereafter termed "analyte") in undiluted original Monkey body fluids, tissue homogenates, secretions or… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Tyrosine Hydroxylase (TH), ELISA Kit

Full Product Name

Monkey Tyrosine Hydroxylase ELISA Kit

Product Gene Name

TH elisa kit

Species Reactivity

Monkey

Assay Type

Quantitative Sandwich

Samples

undiluted original Monkey body fluids, tissue homogenates, secretions or feces samples

Detection Range

0.625 ng/ml - 20 ng/mL

Sensitivity

0.1 ng/mL

Specificity

No significant cross-reactivity or interference between this analyte and analogues is observed.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

58,600 Da

Chromosome Location

Chromosome: 11; NC_000011.9 (2185159..2193035, complement). Location: 11p15.5

OMIM

191290

3D Structure

ModBase 3D Structure for P07101

Other Notes

Small volumes of TH elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TH purchase

MBS004911 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Tyrosine Hydroxylase (TH) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TH. The ELISA analytical biochemical technique of the MBS004911 kit is based on TH antibody-TH antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TH antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TH. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for TH. It may not necessarily be applicable to this product.

NCBI GI #

986909

NCBI GeneID

7054

NCBI Accession #

AAA77650.1

UniProt Primary Accession #

P07101

UniProt Secondary Accession #

Q15585; Q15588; Q15589; B7ZL70

UniProt Related Accession #

P07101

NCBI Official Full Name

tyrosine hydroxylase, partial

NCBI Official Synonym Full Names

tyrosine hydroxylase

NCBI Official Symbol

NCBI Official Synonym Symbols

TYH; DYT14; DYT5b

UniProt Protein Name

Tyrosine 3-monooxygenase

UniProt Synonym Protein Names

Tyrosine 3-hydroxylase

UniProt Gene Name

UniProt Synonym Gene Names

TYH; TH

UniProt Entry Name

TY3H_HUMAN

NCBI Protein Information

tyrosine 3-monooxygenase; dystonia 14; tyrosine 3-hydroxylase

NCBI Summary for TH

The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for TH

TH: an enzyme involved in the conversion of phenylalanine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. Four splice variant isoforms have been described.

Protein type: Oxidoreductase; Vesicle; EC 1.14.16.2; Amino Acid Metabolism - tyrosine; Mitochondrial; Endoplasmic reticulum

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: internal side of plasma membrane; neuron projection; smooth endoplasmic reticulum; mitochondrion; melanosome membrane; dendrite; terminal button; perikaryon; cytosol; synaptic vesicle; cytoplasm; cytoplasmic vesicle; nucleus

Molecular Function: protein domain specific binding; amino acid binding; protein binding; enzyme binding; ferric iron binding; ferrous iron binding; dopamine binding; oxygen binding; tyrosine 3-monooxygenase activity

Biological Process: heart morphogenesis; heart development; response to lipopolysaccharide; dopamine biosynthetic process; phytoalexin metabolic process; norepinephrine biosynthetic process; dopamine biosynthetic process from tyrosine; catecholamine biosynthetic process; response to electrical stimulus; epinephrine biosynthetic process; response to pyrethroid; response to corticosterone stimulus; neurotransmitter biosynthetic process; response to light stimulus; anatomical structure morphogenesis; phthalate metabolic process; mating behavior; social behavior; organ morphogenesis; eye photoreceptor cell development; circadian sleep/wake cycle; response to ethanol; response to zinc ion; cerebral cortex development; response to activity; response to water deprivation; response to peptide hormone stimulus; synaptic transmission, dopaminergic; locomotory behavior; fatty acid metabolic process; response to estradiol stimulus; regulation of heart contraction; response to salt stress; sensory perception of sound; visual perception; glycoside metabolic process; response to nutrient levels; terpene metabolic process; sphingolipid metabolic process; eating behavior; response to amphetamine; multicellular organismal aging; isoquinoline alkaloid metabolic process; response to herbicide; learning; response to ether; synaptic vesicle amine transport; memory; pigmentation; response to hypoxia; embryonic camera-type eye morphogenesis

Disease: Segawa Syndrome, Autosomal Recessive

Research Articles on TH

1. In severe prolonged fetal hypoxia, there was a striking reduction or absence of tyrosine hydroxylase in all the mesencephalic nuclei.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TH elisa kit

Reference Product	PubMed Publications
JUN elisa kit	>507272 publications with TH and JUN
GAL elisa kit	>3081 publications with TH and GAL
FOS elisa kit	>2497 publications with TH and FOS
NGF elisa kit	>1677 publications with TH and NGF
TYR elisa kit	>1499 publications with TH and TYR
DDC elisa kit	>654 publications with TH and DDC
FOSB elisa kit	>93 publications with TH and FOSB
MAPKAPK2 elisa kit	>68 publications with TH and MAPKAPK2
YWHAZ elisa kit	>11 publications with TH and YWHAZ
CAMK2G elisa kit	>5 publications with TH and CAMK2G

Pathways associated with TH elisa kit

Products by Pathway	Pathway Diagram
ATF-2 Transcription Factor Network Pathway antibodies	ATF-2 Transcription Factor Network Pathway Diagram
Alcoholism Pathway antibodies	Alcoholism Pathway Diagram
Alcoholism Pathway antibodies	Alcoholism Pathway Diagram
Alpha-synuclein Signaling Pathway antibodies	Alpha-synuclein Signaling Pathway Diagram
Amine-derived Hormones Pathway antibodies	Amine-derived Hormones Pathway Diagram
Amphetamine Addiction Pathway antibodies	Amphetamine Addiction Pathway Diagram
Amphetamine Addiction Pathway antibodies	Amphetamine Addiction Pathway Diagram
Biogenic Amine Synthesis Pathway antibodies	Biogenic Amine Synthesis Pathway Diagram
Catecholamine Biosynthesis Pathway antibodies	Catecholamine Biosynthesis Pathway Diagram
Catecholamine Biosynthesis, Tyrosine => Dopamine => Noradrenaline => Adrenaline Pathway antibodies	Catecholamine Biosynthesis, Tyrosine => Dopamine => Noradrenaline => Adrenaline Pathway Diagram

Diseases associated with TH elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>1162433 publications with TH and Neoplasms
Nervous System Diseases Antibodies	>850549 publications with TH and Nervous System Diseases
Heart Diseases Antibodies	>468118 publications with TH and Heart Diseases
Brain Diseases Antibodies	>404506 publications with TH and Brain Diseases
Pain Antibodies	>308996 publications with TH and Pain
Kidney Diseases Antibodies	>203409 publications with TH and Kidney Diseases
Hypertension Antibodies	>167734 publications with TH and Hypertension
Inflammation Antibodies	>165137 publications with TH and Inflammation
Drug Toxicity Antibodies	>128883 publications with TH and Drug Toxicity
Necrosis Antibodies	>107339 publications with TH and Necrosis

Organs/Tissues associated with TH elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>271975 publications with TH and Brain
Eye Antibodies	>141823 publications with TH and Eye
Nerve Antibodies	>123121 publications with TH and Nerve
Mouth Antibodies	>100287 publications with TH and Mouth
Pancreas Antibodies	>40085 publications with TH and Pancreas
Adrenal Gland Antibodies	>19166 publications with TH and Adrenal Gland
Embryonic Tissue Antibodies	>16090 publications with TH and Embryonic Tissue
Placenta Antibodies	>8729 publications with TH and Placenta
Uncharacterized Tissue Antibodies	>98 publications with TH and Uncharacterized Tissue