Nfl (Neurofilament Light Chain) (NfL) ELISA Kit for Human

Neurofilaments are intermediate diameter (10nm) filaments that are located in neurons specifically. They are usually composed of three mid-diameter filament proteins, NfL, NfM, and NfH, and are associated with the maintenance of the inner diameter of nerves. Neurofilaments are expressed specifically in nerves and their expression increases after nerve injury from neurological or traumatic diseases. Therefore, they are attracting attention as biomarkers that reflect the state of neurological disorders.

Small volumes of NfL elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS492201 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the NfL (Neurofilament light chain) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing NfL. The ELISA analytical biochemical technique of the MBS492201 kit is based on NfL antibody-NfL antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NfL antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NfL. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).