Rabbit Anti-PANK4 Polyclonal Antibody – Cat# MBS500065

PANK4 Antibody – Rabbit Polyclonal

Name: PANK4 Antibody; Polyclonal; Rabbit; Rat/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS500065
Price: 495 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS500065

Pantothenate kinase, PanK, is a vital regulatory enzyme for coenzyme A (CoA) biosynthesis, phosphorylating pantothenate (vitamin B5) to 4'-phosphopantothenate, then quickly transforming to CoA which is an essential component for fatty acid metabolism (Abiko,… More details

$495 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PanK4, Polyclonal Antibody

Full Product Name

PanK4 (Thr63)

Product Gene Name

anti-PANK4 antibody

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Hamster, Rat
Predicted: Mouse

Form/Format

100 ul in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol.

Purity/Purification

Affinity Purified from Pooled Serum

Preparation and Storage

Store at -20 degree C

Molecular Weight

~86 kDa

3D Structure

ModBase 3D Structure for Q80YV4

Immunogen

Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr63 conjugated to KLH
Immunogen Species||Mouse

Purification Note

The antibody is prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.

Product Categories/Family for anti-PANK4 antibody

Signal Transduction

Applications Tested/Suitable for anti-PANK4 antibody

Western Blot (WB)

Application Notes for anti-PANK4 antibody

WB: 1:1000

Other Notes

Small volumes of anti-PANK4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PANK4 purchase

MBS500065 is an antibody targeting PANK4. Also known as PanK4 (Thr63). Reactive in Hamster, Rat
Predicted: Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PANK4. It may not necessarily be applicable to this product.

NCBI GI #

802083995

NCBI GeneID

269614

NCBI Accession #

NP_001292733.1

UniProt Primary Accession #

Q80YV4

UniProt Secondary Accession #

Q7M751; Q8BQE9; B1AZN5; B1AZN6

UniProt Related Accession #

Q80YV4

GenBank Nucleotide #

NM_001305804.1

NCBI Official Full Name

pantothenate kinase 4 isoform 1

NCBI Official Synonym Full Names

pantothenate kinase 4

NCBI Official Symbol

Pank4

NCBI Official Synonym Symbols

R75150; D030031I12Rik

UniProt Protein Name

Pantothenate kinase 4

UniProt Synonym Protein Names

Pantothenic acid kinase 4

Protein Family

Pantothenate kinase

UniProt Gene Name

Pank4

UniProt Synonym Gene Names

mPanK4

NCBI Protein Information

pantothenate kinase 4

UniProt Comments for PANK4

PANK4: a pantothenate kinase that catalyzes the first committed step in the biosynthesis of coenzyme A, an essential cofactor in cellular metabolism. PANK4 is ubiquitously expressed but is enriched in muscle. Plays a role in the physiological regulation of the intracellular CoA concentration. Regulated by feedback inhibition by CoA and its thioesters. Interacts with M2-type pyruvate kinase (PKM2) and may modulate glucose metabolism through regulating the activity of PKM2. Expression is up-regulated by high glucose concentrations.

Protein type: Cofactor and Vitamin Metabolism - pantothenate and CoA biosynthesis; EC 2.7.1.33; Kinase, other

Chromosomal Location of Human Ortholog: 4|4 E2

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PANK4 antibody

Products by Pathway	Pathway Diagram
Coenzyme A Biosynthesis, Pantothenate => CoA Pathway antibodies	Coenzyme A Biosynthesis, Pantothenate => CoA Pathway Diagram
Coenzyme A Biosynthesis, Pantothenate => CoA Pathway antibodies	Coenzyme A Biosynthesis, Pantothenate => CoA Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Pantothenate And CoA Biosynthesis Pathway antibodies	Pantothenate And CoA Biosynthesis Pathway Diagram
Pantothenate And CoA Biosynthesis Pathway antibodies	Pantothenate And CoA Biosynthesis Pathway Diagram

Diseases associated with anti-PANK4 antibody

Disease Name	Pubmed Publications
Disease Models, Animal Antibodies	>1 publications with PANK4 and Disease Models, Animal
Nervous System Diseases Antibodies	>1 publications with PANK4 and Nervous System Diseases

Organs/Tissues associated with anti-PANK4 antibody

Organ/Tissue Name	Pubmed Publications
Pancreas Antibodies	>1 publications with PANK4 and Pancreas