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Arginase I/Liver Arginase (ARG1) Antibody – Chicken Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS500082

Arginase I, a cytosolic enzyme, is highly expressed in the liver and is a component of the urea cycle (Jenkinson et al, 1996). There are two isoforms of arginase, both catalyze the conversion of arginine to ornithine and urea, but differ based on subcellular… More details

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Product Overview

Online Datasheet in PDF
Product Name
Arginase I/Liver Arginase (ARG1), Polyclonal Antibody
Full Product Name
Anti-Arginase I/Liver Arginase (ARG1) Antibody
Product Gene Name
anti-ARG1 antibody
Product Synonym Names
Arginase I (ARG1)
Clonality
Polyclonal
Host
Chicken
Species Reactivity
Guinea Pig, Human, Mouse, Rat
Form/Format
100 ul in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol.
Purity/Purification
Total IgY Fraction
Specificity
Specific for endogenous levels of the ~35-38 kDa arginase I protein.
Preparation and Storage
Store at -20 degree C in undiluted aliquots as aliquots may be taken without freeze/thawing due to presence of 50% glycerol stable for at least 1 year.
Molecular Weight
~35,38 kDa
3D Structure
ModBase 3D Structure for P07824
Immunogen Species
Rat
Immunogen Information
Full-length recombinant rat arginase I.
Antigen
Full-length recombinant rat liver arginase I expressed in and purified from E Coli.
Quality Control Tests
Western blots performed on each lot.
Applications Tested/Suitable for anti-ARG1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ARG1 antibody
WB: 1:1000
IHC: 1:500

Western Blot (WB) of anti-ARG1 antibody

Western blot of mouse liver lysate showing specific immunolabeling of the ~35, 38 kDa arginase I protein.
Chicken Anti-ARG1 Polyclonal Antibody – Cat# MBS500082

Product References and Citations for anti-ARG1 antibody

1. Morris SM, Kepka-Lenhart D, Chen LC. Differential regulation of arginases and inducible nitric oxide synthase in murine macrophage cells. Am J Physiol 275(5 Pt 1):E740-7 (1998). 2. Poljakovic M, Porter DW, Millecchia L, Kepka-Lenhart D, Beighley C, Wolfarth MG, Castranova V, Morris SM. Celland Isoform-specific increases in arginase expression in acute silica-induced pulmonary inflammation. J Toxicol Environ Health A 15;70(2):118-127 (2007). 3. Jenkinson CP, Grody WW, Cederbaum SD. Comparative properties of arginases. Comp. Biochem. Physiol B Biochem Mol Biol 114B:107-132 (1996).

Other Notes

Small volumes of anti-ARG1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARG1 purchase

MBS500082 is an antibody targeting ARG1. Also known as Anti-Arginase I/Liver Arginase (ARG1) Antibody. Reactive in Guinea Pig, Human, Mouse, Rat. Host: Chicken.

Additional Details

NCBI/Uniprot data below describe general gene information for ARG1. It may not necessarily be applicable to this product.

NCBI GI #
319754464
NCBI Accession #
ADV66221.1
UniProt Primary Accession #
P07824
NCBI Official Full Name
arginase
UniProt Protein Name
Arginase-1
UniProt Synonym Protein Names
Liver-type arginase; Type I arginase
Protein Family
Arginase
UniProt Gene Name
Arg1
UniProt Entry Name
ARGI1_RAT

UniProt Comments for ARG1

ARG1: Homotrimer. By arginine or homoarginine. Belongs to the arginase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; EC 3.5.3.1; Amino Acid Metabolism - arginine and proline

Cellular Component: extracellular space; mitochondrial outer membrane; neuron projection; cell soma; cytoplasm; nucleus

Molecular Function: manganese ion binding; arginase activity

Biological Process: mammary gland involution; response to peptide hormone stimulus; maternal process involved in pregnancy; response to lipopolysaccharide; female pregnancy; response to vitamin A; response to selenium ion; response to vitamin E; response to methylmercury; response to wounding; response to axon injury; collagen biosynthetic process; aging; response to drug; response to herbicide; liver development; response to amino acid stimulus; response to manganese ion; response to cadmium ion; arginine metabolic process; response to zinc ion; response to steroid hormone stimulus; arginine catabolic process to ornithine; positive regulation of endothelial cell proliferation; lung development; response to amine stimulus; urea cycle
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ARG1 antibody

 Reference Product  PubMed Publications
 Nos2 antibody  >56 publications with ARG1 and Nos2
 Nos3 antibody  >14 publications with ARG1 and Nos3
 Nos1 antibody  >6 publications with ARG1 and Nos1
 Asl antibody  >6 publications with ARG1 and Asl
 Otc antibody  >5 publications with ARG1 and Otc
 Slc25a15 antibody  >2 publications with ARG1 and Slc25a15
 Oat antibody  >2 publications with ARG1 and Oat

Pathways associated with anti-ARG1 antibody

 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Polyamine Biosynthesis, Arginine => Ornithine => Putrescine Pathway antibodies  Polyamine Biosynthesis, Arginine => Ornithine => Putrescine Pathway Diagram

Diseases associated with anti-ARG1 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >107 publications with ARG1 and Inflammation
 Disease Models, Animal Antibodies  >62 publications with ARG1 and Disease Models, Animal
 Lung Diseases Antibodies  >60 publications with ARG1 and Lung Diseases
 Immune System Diseases Antibodies  >44 publications with ARG1 and Immune System Diseases
 Necrosis Antibodies  >34 publications with ARG1 and Necrosis
 Cardiovascular Diseases Antibodies  >32 publications with ARG1 and Cardiovascular Diseases
 Asthma Antibodies  >28 publications with ARG1 and Asthma
 Fibrosis Antibodies  >22 publications with ARG1 and Fibrosis
 Lung Neoplasms Antibodies  >21 publications with ARG1 and Lung Neoplasms
 Liver Diseases Antibodies  >20 publications with ARG1 and Liver Diseases

Organs/Tissues associated with anti-ARG1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >86 publications with ARG1 and Brain
 Lung Antibodies  >84 publications with ARG1 and Lung
 Liver Antibodies  >59 publications with ARG1 and Liver
 Small Intestine Antibodies  >38 publications with ARG1 and Small Intestine
 Eye Antibodies  >26 publications with ARG1 and Eye
 Spleen Antibodies  >25 publications with ARG1 and Spleen
 Colon Antibodies  >21 publications with ARG1 and Colon
 Pancreas Antibodies  >8 publications with ARG1 and Pancreas
 Connective Tissue Antibodies  >7 publications with ARG1 and Connective Tissue
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