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p23 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS505068

The small capsid antigen p23 is a tegument protein. Although p23 has IgG sensitivity and intensity of reaction similar to those of p18, its IgM reactivity is a bit restricted. With respect to detection of IgG antibodies, p23 and p18 have similar… More details

$1195 / 1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
p23, Recombinant Protein
Full Product Name
Recombinant capsid antigen p23 for Epstein-barr virus
Product Gene Name
p23 recombinant protein
Product Synonym Names
p23 (VCA); BLRF2
Form/Format
Dry powder (lyophilized)
Purity/Purification
>95% in a SDS-PAGE
Specificity
The protein is immunoreactive against seropositive individuals to Epstein-Barr virus infection
Preparation and Storage
Lyophilized protein is shipped with on ice packs. Upon arrival, it should be stored at 20 degree C to -80 degree C. Aliquot after reconstitution in order to avoid repeated freezing and thawing cycles and store at 20 degree C to -80 degree C.
Molecular Weight
16,476 Da
OMIM
L24804 mRNA
Organism
EBV
IVD
Seroidentification of infectious mononucleosis associated to EBV and primary acute infections in immunocompromised individuals
Reconstitution
For lyophilized proteins: with 0.04 ml of sterile double-distilled water (lot specific) for a final concentration of 1.59 mg/ml (lot specific). The protein will be at pH 8.

Product Categories/Family for p23 recombinant protein

Viruses
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of p23 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for p23 purchase

MBS505068 is a recombinant protein targeting p23. Also known as Recombinant capsid antigen p23 for Epstein-barr virus.

Additional Details

NCBI/Uniprot data below describe general gene information for p23. It may not necessarily be applicable to this product.

NCBI GI #
438652
NCBI GeneID
10728
NCBI Accession #
AAA18537.1
UniProt Secondary Accession #
Q8WU70; A8K7D0; B4DHP2; B4DP11; B4DP21
UniProt Related Accession #
Q15185
NCBI Official Full Name
p23
NCBI Official Synonym Full Names
prostaglandin E synthase 3
NCBI Official Symbol
PTGES3
NCBI Official Synonym Symbols
P23; TEBP; cPGES
UniProt Protein Name
Prostaglandin E synthase 3
UniProt Synonym Protein Names
Cytosolic prostaglandin E2 synthase; cPGES; Hsp90 co-chaperone; Progesterone receptor complex p23; Telomerase-binding protein p23
Protein Family
Protein
UniProt Gene Name
PTGES3
UniProt Synonym Gene Names
P23; TEBP; cPGES
NCBI Protein Information
prostaglandin E synthase 3

NCBI Summary for p23

This gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). This protein functions as a co-chaperone with heat shock protein 90 (HSP90), localizing to response elements in DNA and disrupting transcriptional activation complexes. Alternative splicing results in multiple transcript variants. There are multiple pseudogenes of this gene on several different chromosomes. [provided by RefSeq, Feb 2016]
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UniProt Comments for p23

TEBP: Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor- mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Belongs to the p23/wos2 family.

Protein type: Chaperone; EC 5.3.99.3; Isomerase; Nuclear receptor co-regulator; Transferase

Chromosomal Location of Human Ortholog: 12q13.3|12

Cellular Component: chromosome, telomeric region; cytosol; nucleoplasm; nucleus; protein complex; telomerase holoenzyme complex

Molecular Function: Hsp90 protein binding; prostaglandin-E synthase activity; protein binding; telomerase activity; unfolded protein binding

Biological Process: chaperone-mediated protein complex assembly; cyclooxygenase pathway; positive regulation of phosphorylation; positive regulation of telomerase activity; prostaglandin biosynthetic process; protein stabilization; signal transduction; telomere maintenance; telomere maintenance via telomerase; xenobiotic metabolic process
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Research Articles on p23

1. dysregulation of GR, MR, FKBP5, and PTGES3 in autistic spectrum disorder (ASD) and suggest a possible role of inflammation in altered GR function in ASD.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with p23 recombinant protein

 Reference Product  PubMed Publications
 PTGS2 recombinant protein  >8 publications with p23 and PTGS2
 PTGES2 recombinant protein  >8 publications with p23 and PTGES2
 PTGS1 recombinant protein  >6 publications with p23 and PTGS1
 STIP1 recombinant protein  >3 publications with p23 and STIP1
 HSP90AA1 recombinant protein  >3 publications with p23 and HSP90AA1
 FKBP4 recombinant protein  >2 publications with p23 and FKBP4

Pathways associated with p23 recombinant protein

 Products by Pathway  Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Aryl Hydrocarbon Receptor Pathway antibodies  Aryl Hydrocarbon Receptor Pathway Diagram
 Aryl Hydrocarbon Receptor Signalling Pathway antibodies  Aryl Hydrocarbon Receptor Signalling Pathway Diagram
 Attenuation Phase Pathway antibodies  Attenuation Phase Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 C20 Prostanoid Biosynthesis Pathway antibodies  C20 Prostanoid Biosynthesis Pathway Diagram
 C20 Prostanoid Biosynthesis Pathway antibodies  C20 Prostanoid Biosynthesis Pathway Diagram
 Cellular Response To Heat Stress Pathway antibodies  Cellular Response To Heat Stress Pathway Diagram

Diseases associated with p23 recombinant protein

 Disease Name  Pubmed Publications
 Lung Diseases Antibodies  >2 publications with p23 and Lung Diseases
 Carcinoma Antibodies  >2 publications with p23 and Carcinoma
 Hypertrophy Antibodies  >1 publications with p23 and Hypertrophy
 Cell Transformation, Neoplastic Antibodies  >1 publications with p23 and Cell Transformation, Neoplastic
 Heart Diseases Antibodies  >1 publications with p23 and Heart Diseases
 Liver Neoplasms Antibodies  >1 publications with p23 and Liver Neoplasms
 Immune System Diseases Antibodies  >1 publications with p23 and Immune System Diseases
 Neoplasm Metastasis Antibodies  >1 publications with p23 and Neoplasm Metastasis
 Cardiomegaly Antibodies  >1 publications with p23 and Cardiomegaly
 Lung Neoplasms Antibodies  >1 publications with p23 and Lung Neoplasms

Organs/Tissues associated with p23 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >4 publications with p23 and Lung
 Brain Antibodies  >4 publications with p23 and Brain
 Uterus Antibodies  >3 publications with p23 and Uterus
 Heart Antibodies  >2 publications with p23 and Heart
 Liver Antibodies  >2 publications with p23 and Liver
 Vascular Antibodies  >2 publications with p23 and Vascular
 Ovary Antibodies  >2 publications with p23 and Ovary
 Bone Antibodies  >1 publications with p23 and Bone
 Blood Antibodies  >1 publications with p23 and Blood
 Muscle Antibodies  >1 publications with p23 and Muscle
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