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TP53RK Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS515194

Recombinant full-length human TP53RK was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: TP53RK or TP53 regulating kinase and also called PRPK (p53-related protein kinase) is the human homologue of yeast Bud32.… More details

$350 / 0.02 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TP53RK, Recombinant Protein
Full Product Name
TP53RK recombinant protein
Product Synonym Gene Name
BUD32; C20orf64; dJ101A2; Nori-2; Nori-2p
Product Synonym Names
BUD32; C20orf64; dJ101A2; Nori-2; Nori-2p
Host
Sf9 insect cells
Form/Format
50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Preparation and Storage
Store product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight
~55 kDa
Chromosome Location
Chromosome: 20; NC_000020.10 (45313004..45318301, complement). Location: 20q13.2
OMIM
608679
3D Structure
ModBase 3D Structure for Q96S44
Type
Recombinant Fusion Protein
Species
Human
Tag Information
GST tag
Expression System
Sf9 insect cells using baculovirus
Source Note
Recombinant full-length human TP53RK was expressed by baculovirus in Sf9 insect cells
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Applications Tested/Suitable for TP53RK recombinant protein
Western Blot (WB)

Product References and Citations for TP53RK recombinant protein

1. Abe, Y.et.al: Cloning and characterization of a p53-related protein kinase expressed in interleukin-2-activated cytotoxic T-cells, epithelial tumor cell lines, and the testes. J. Biol. Chem. 276: 44003-44011, 2001.
2. Miyoshi, A.et.al: Identification of CGI-121, a novel PRPK (p53-related protein kinase)-binding protein. Biochem. Biophys. Res. Commun. 303: 399-405, 2003.

Other Notes

Small volumes of TP53RK recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TP53RK purchase

MBS515194 is a recombinant protein targeting TP53RK. Host: Sf9 insect cells.

Additional Details

NCBI/Uniprot data below describe general gene information for TP53RK. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Homo sapiens TP53 regulating kinase (TP53RK), mRNA
NCBI Official Synonym Full Names
TP53 regulating kinase
NCBI Official Symbol
TP53RK
NCBI Official Synonym Symbols
PRPK; BUD32; Nori-2; Nori-2p; dJ101A2; C20orf64
UniProt Protein Name
TP53-regulating kinase
UniProt Synonym Protein Names
Nori-2; p53-related protein kinase
UniProt Gene Name
TP53RK
UniProt Synonym Gene Names
C20orf64; PRPK
UniProt Entry Name
PRPK_HUMAN
NCBI Protein Information
TP53-regulating kinase; p53-related protein kinase

UniProt Comments for TP53RK

Function: Protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation. Ref.1

Catalytic activity: ATP + a protein = ADP + a phosphoprotein.

Subunit structure: Interacts with TPRKB. Ref.7

Subcellular location: Nucleus.

Tissue specificity: Highly expressed in testis. Weakly expressed in heart kidney and spleen.

Sequence similarities: Belongs to the protein kinase superfamily.Contains 1 protein kinase domain.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TP53RK recombinant protein

 Reference Product  PubMed Publications
 TP53 recombinant protein  >1 publications with TP53RK and TP53

Organs/Tissues associated with TP53RK recombinant protein

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