SCYL3 Recombinant Protein

Name: SCYL3 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS515257
Price: 350 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS515257

Recombinant human SCYL3 (2-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: SCYL3 encodes a protein with a kinase domain and four HEAT repeats which interact with the C-terminal domain of ezrin, an ERM… More details

$350 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SCYL3, Recombinant Protein

Full Product Name

SCYL3 recombinant protein

Product Gene Name

SCYL3 recombinant protein

Product Synonym Gene Name

PACE-1; PACE1; RP1-97P20.2

Product Synonym Names

PACE-1; PACE1; RP1-97P20.2

Host

Sf9 insect cells

Form/Format

50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Preparation and Storage

Store product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Molecular Weight

~110 kDa

Chromosome Location

Chromosome: 1; NC_000001.10 (169822215..169863100, complement). Location: 1q24.2

OMIM

608192

3D Structure

ModBase 3D Structure for Q8IZE3

Type

Recombinant Fusion Protein

Species

Human

Tag Information

GST tag

Expression System

Sf9 insect cells using baculovirus

Source Note

Recombinant human SCYL3 (2-end) was expressed by baculovirus in Sf9 insect cells

Dry Ice Shipment

Extra charge fee may add to your shipping cost as dry ice is required to ship this product.

Product Categories/Family for SCYL3 recombinant protein

Cellular Proteins; Signaling Proteins - Cellular Proteins

Applications Tested/Suitable for SCYL3 recombinant protein

Western Blot (WB)

Product References and Citations for SCYL3 recombinant protein

1. Sullivan, A. et.al: PACE-1, a novel protein that interacts with the C-terminal domain of ezrin. Exp. Cell Res. 284: 224-238, 2003.

Other Notes

Small volumes of SCYL3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SCYL3 purchase

MBS515257 is a recombinant protein targeting SCYL3. Host: Sf9 insect cells.

Additional Details

NCBI/Uniprot data below describe general gene information for SCYL3. It may not necessarily be applicable to this product.

NCBI GI #

15779206

NCBI GeneID

57147

NCBI Accession #

BC014662

UniProt Primary Accession #

Q8IZE3

UniProt Secondary Accession #

Q5THA6; Q5THA8; Q8IZN9; Q96C56; Q9UBK6; A8K8Z2

UniProt Related Accession #

Q8IZE3

NCBI Official Full Name

Homo sapiens SCY1-like 3 (S. cerevisiae), mRNA

NCBI Official Synonym Full Names

SCY1-like 3 (S. cerevisiae)

NCBI Official Symbol

SCYL3

NCBI Official Synonym Symbols

PACE1; PACE-1

UniProt Protein Name

Protein-associating with the carboxyl-terminal domain of ezrin

UniProt Synonym Protein Names

Ezrin-binding protein PACE-1; SCY1-like protein 3

Protein Family

Protein-associating with the carboxyl-terminal domain of ezrin

UniProt Gene Name

SCYL3

UniProt Synonym Gene Names

PACE1

UniProt Entry Name

PACE1_HUMAN

NCBI Protein Information

protein-associating with the carboxyl-terminal domain of ezrin; SCY1-like protein 3; ezrin-binding protein PACE-1; ezrin-binding partner PACE-1 (PACE-1)

NCBI Summary for SCYL3

This gene encodes a protein with a kinase domain and four HEAT repeats. The encoded protein interacts with the C-terminal domain of ezrin, an ERM protein, and may play a role in cell adhesion and migration. Alternative splicing results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Jun 2012]

UniProt Comments for SCYL3

Function: May play a role in regulating cell adhesion/migration complexes in migrating cells. Ref.1

Subunit structure: Interacts with EZR/VIL2 C-terminal domain. Ref.1

Subcellular location: Cytoplasm. Golgi apparatus. Cell projection › lamellipodium. Note: Colocalized with EZR/VIL2, actin and CD44 in lamellipodia. Ref.1

Tissue specificity: Ubiquitously expressed. Ref.1

Domain: The protein kinase domain is predicted to be catalytically inactive.

Post-translational modification: May be myristoylated; myristoylation may target it to Golgi compartment.Phosphorylated. Ref.1

Sequence similarities: Belongs to the protein kinase superfamily.Contains 4 HEAT repeats.Contains 1 protein kinase domain.

Research Articles on SCYL3

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.