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CDK11B Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS515466

Description: Recombinant full-length human CDK11B (CDC2L1) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: CDC2L1 is a member of the p34Cdc2 protein kinase family. p34Cdc2 protein kinase family is known to… More details

$350 / 0.02 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CDK11B, Recombinant Protein
Full Product Name
CDK11B (CDC2L1) Protein
Product Synonym Gene Name
CDC2L1; CDK11-p110; CDK11-p46; p58CDC2L1; CLK-1; CDK11-p58; p58CLK-1; p58; PK58
Host
Sf9 insect cells using baculovirus
Form/Format
50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Preparation and Storage
Store product at -70 degree C.
For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature.
For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight
~135kDa
Sequence Positions
Full Length
OMIM
M37712 mRNA
3D Structure
ModBase 3D Structure for P21127
Species
Human
Tag
GST tag
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Applications Tested/Suitable for CDK11B recombinant protein
Western Blot (WB)

Product References and Citations for CDK11B recombinant protein

1. Bunnell, B. et.al: Elevated expression of a p58 protein kinase leads to changes in the CHO cell cycle. Proc. Nat. Acad. Sci. 87: 7 Note: Erratum: Proc. Nat. Acad. Sci. 88: 2612 only, 1991. 2. Xiang, J. et.al: Molecular cloning and expression of alternatively spliced PITSLRE protein kinase isoforms. J. Biol. Chem. 269: 15786-15794, 1994.

Other Notes

Small volumes of CDK11B recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDK11B purchase

MBS515466 is a recombinant protein targeting CDK11B. Also known as CDK11B (CDC2L1) Protein. Host: Sf9 insect cells using baculovirus.

Additional Details

NCBI/Uniprot data below describe general gene information for CDK11B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Homo sapiens cyclin dependent kinase 11B (CDK11B), transcript variant 2, mRNA
NCBI Official Synonym Full Names
cyclin dependent kinase 11B
NCBI Official Symbol
CDK11B
NCBI Official Synonym Symbols
p58; PK58; CDK11; CLK-1; CDC2L1; PITSLREA; p58CLK-1; CDK11-p46; CDK11-p58; p58CDC2L1; CDK11-p110
UniProt Protein Name
Cyclin-dependent kinase 11B
UniProt Synonym Protein Names
Cell division cycle 2-like protein kinase 1; CLK-1; Cell division protein kinase 11B; Galactosyltransferase-associated protein kinase p58/GTA; PITSLRE serine/threonine-protein kinase CDC2L1; p58 CLK-1
UniProt Gene Name
CDK11B
UniProt Synonym Gene Names
CDC2L1; CDK11; PITSLREA; PK58; CLK-1
NCBI Protein Information
cyclin-dependent kinase 11B

NCBI Summary for CDK11B

This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
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UniProt Comments for CDK11B

Plays multiple roles in cell cycle progression, cytokinesis and apoptosis. Involved in pre-mRNA splicing in a kinase activity-dependent manner. Isoform 7 may act as a negative regulator of normal cell cycle progression.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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