• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CDK3/Cycline2 (CDK3) Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS515475

Description: Recombinant full-length human CDK3 and Cyclin E2 were co-expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag on both proteins.Scientific Background: CDK3/CyclinE is a member of the cyclin-dependent protein kinase family and… More details

$445 / 0.01 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CDK3/CyclinE2, Recombinant Protein
Full Product Name
CDK3/CyclinE2, Active
Product Gene Name
CDK3 recombinant protein
Product Synonym Gene Name
CCNE1
Product Synonym Names
CDK3/CyclinE1, Active
Host
Sf9 insect cells using baculovirus
Form/Format
50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Preparation and Storage
Store product at -70 degree C.
For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature.
For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight
~60 kDa; ~72 kDa
Sequence Positions
Full length
OMIM
X66357 mRNA
Species
Human
Tag
GST tag
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.

Product Categories/Family for CDK3 recombinant protein

Enzymes; Active Kinases
Applications Tested/Suitable for CDK3 recombinant protein
Kinase Assay, Western Blot (WB)

Testing Data of CDK3 recombinant protein

CDK3 Recombinant Protein – Cat# MBS515475

Testing Data #2 of CDK3 recombinant protein

CDK3 Recombinant Protein, Testing Data #2 – Cat# MBS515475

Product References and Citations for CDK3 recombinant protein

1. Bullrich, F. et al: Chromosomal mapping of members of the cdc2 family of protein kinases, cdk3, cdk6, PISSLRE, and PITALRE, and a cdk inhibitor, p27-Kip1, to regions involved in human cancer. Cancer Res. 55: 1199-1205, 1995. 2. Ye, X. et al: A premature-termination mutation in the Mus musculus cyclin-dependent kinase 3 gene. Proc. Nat. Acad. Sci. 98: 1682-1686, 2001.

Other Notes

Small volumes of CDK3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDK3 purchase

MBS515475 is a recombinant protein targeting CDK3. Also known as CDK3/CyclinE2, Active. Host: Sf9 insect cells using baculovirus.

Additional Details

NCBI/Uniprot data below describe general gene information for CDK3. It may not necessarily be applicable to this product.

NCBI GI #
164519034
NCBI GeneID
1018
NCBI Accession #
NM_001258.2
UniProt Related Accession #
Q00526
GenBank Nucleotide #
NM_001258
NCBI Official Full Name
Homo sapiens cyclin dependent kinase 3 (CDK3), mRNA
NCBI Official Synonym Full Names
cyclin dependent kinase 3
NCBI Official Symbol
CDK3
UniProt Protein Name
Cyclin-dependent kinase 3
UniProt Synonym Protein Names
Cell division protein kinase 3
Protein Family
Cyclin-dependent kinase
UniProt Gene Name
CDK3
UniProt Synonym Gene Names
CDKN3
NCBI Protein Information
cyclin-dependent kinase 3

NCBI Summary for CDK3

This gene encodes a member of the cyclin-dependent protein kinase family. The protein promotes entry into S phase, in part by activating members of the E2F family of transcription factors. The protein also associates with cyclin C and phosphorylates the retinoblastoma 1 protein to promote exit from G0. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for CDK3

CDK3: a protein kinase of the CDK family. May be involved in cell cycle control. Can phosphorylate histone H1.

Protein type: CDK family; CDK/CDK1 subfamily; CDK1 subfamily; CMGC group; Cell cycle regulation; EC 2.7.11.22; Kinase, protein; Protein kinase, CMGC; Protein kinase, Ser/Thr (non-receptor)

Chromosomal Location of Human Ortholog: 17q25.1

Cellular Component: cyclin-dependent protein kinase holoenzyme complex; cytoplasm; nucleus

Molecular Function: cyclin binding; cyclin-dependent protein kinase activity; protein binding

Biological Process: cell proliferation; G0 to G1 transition; G1/S transition of mitotic cell cycle; multicellular organismal development; positive regulation of cell proliferation; protein amino acid phosphorylation; regulation of G2/M transition of mitotic cell cycle; regulation of gene expression; response to DNA damage stimulus; response to organic substance; signal transduction
Show more

Research Articles on CDK3

1. High Cdk3-promoted epithelial-mesenchymal transition through activating AP-1 is involved in colorectal cancer metastasis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CDK3 recombinant protein

 Reference Product  PubMed Publications
 CDKN1A recombinant protein  >8 publications with CDK3 and CDKN1A
 CABLES1 recombinant protein  >7 publications with CDK3 and CABLES1
 CCNC recombinant protein  >5 publications with CDK3 and CCNC
 JUN recombinant protein  >4 publications with CDK3 and JUN
 E2F1 recombinant protein  >3 publications with CDK3 and E2F1
 CCNE2 recombinant protein  >2 publications with CDK3 and CCNE2
 CDC37 recombinant protein  >1 publications with CDK3 and CDC37
 ATF1 recombinant protein  >1 publications with CDK3 and ATF1
 CCNI recombinant protein  >1 publications with CDK3 and CCNI
 CDKN3 recombinant protein  >1 publications with CDK3 and CDKN3

Diseases associated with CDK3 recombinant protein

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >2 publications with CDK3 and Necrosis
 Adenocarcinoma Antibodies  >2 publications with CDK3 and Adenocarcinoma
 Liver Diseases Antibodies  >1 publications with CDK3 and Liver Diseases
 Cardiovascular Diseases Antibodies  >1 publications with CDK3 and Cardiovascular Diseases
 Brain Diseases Antibodies  >1 publications with CDK3 and Brain Diseases
 Pancreatic Neoplasms Antibodies  >1 publications with CDK3 and Pancreatic Neoplasms
 Lung Diseases Antibodies  >1 publications with CDK3 and Lung Diseases
 Carcinoma, Hepatocellular Antibodies  >1 publications with CDK3 and Carcinoma, Hepatocellular
 Hyperglycemia Antibodies  >1 publications with CDK3 and Hyperglycemia

Organs/Tissues associated with CDK3 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >5 publications with CDK3 and Blood
 Brain Antibodies  >3 publications with CDK3 and Brain
 Ovary Antibodies  >2 publications with CDK3 and Ovary
 Eye Antibodies  >1 publications with CDK3 and Eye
 Lung Antibodies  >1 publications with CDK3 and Lung
 Lymph Node Antibodies  >1 publications with CDK3 and Lymph Node
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000