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TAU-441 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS515697

Description: Recombinant human tag-free Tau-441 (A152T) was expressed in E Coli cells.Scientific Background: Tau-441 or Tau-F is a member of the Tau family of proteins which function to stabilize the microtubules by binding to them. Tau proteins are subject… More details

$320 / 0.02 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Tau-441, Recombinant Protein
Full Product Name
Tau-441 (A152T) Protein
Product Gene Name
Tau-441 recombinant protein
Product Synonym Gene Name
Tau-F; (N2R4); Tau-4; MAPT; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17; FLJ31424; MGC138549
Host
E Coli
Form/Format
50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Preparation and Storage
Store product at -70 degree C.
For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature.
For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight
64 kDa (45.8 kDa by MW calculation)
Sequence Positions
A152T
OMIM
J03778 mRNA
3D Structure
ModBase 3D Structure for P10636-8
Species
Human
Tag
Tag-free
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.

Product Categories/Family for Tau-441 recombinant protein

Signaling Proteins; Tau Proteins
Applications Tested/Suitable for Tau-441 recombinant protein
Kinase Assay, Western Blot (WB)

Testing Data of Tau-441 recombinant protein

TAU-441 Recombinant Protein – Cat# MBS515697

Testing Data #2 of Tau-441 recombinant protein

TAU-441 Recombinant Protein, Testing Data #2 – Cat# MBS515697

Product References and Citations for Tau-441 recombinant protein

1. Zilka, N., et al. Truncated tau from sporadic Alzheimer's disease suffices to drive neurofibrillary degeneration in vivo. FEBS Lett. 2006; 508: 3582-3588. 2. Rial, A. et al: Calcium Dyshomeostasis in -Amyloid and Tau-bearing Skeletal Myotubes. J. Biol. Chem., 2004; 279: 3524-53532.

Other Notes

Small volumes of Tau-441 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Tau-441 purchase

MBS515697 is a recombinant protein targeting Tau-441. Also known as Tau-441 (A152T) Protein. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for Tau-441. It may not necessarily be applicable to this product.

UniProt Primary Accession #
P10636-8
UniProt Secondary Accession #
P18518; Q14799; Q15549; Q15550; Q15551; Q1RMF6; Q53YB1; Q5CZI7; Q5XWF0; Q6QT54; Q9UDJ3
UniProt Protein Name
Microtubule-associated protein tau
UniProt Synonym Protein Names
Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau
UniProt Gene Name
MAPT
UniProt Synonym Gene Names
MAPTL; MTBT1; TAU; PHF-tau

UniProt Comments for Tau-441

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Tau-441 recombinant protein

 Reference Product  PubMed Publications
 GSK3B recombinant protein  >76 publications with Tau-441 and GSK3B
 CDK5 recombinant protein  >43 publications with Tau-441 and CDK5
 CASP3 recombinant protein  >37 publications with Tau-441 and CASP3
 CDK5R1 recombinant protein  >5 publications with Tau-441 and CDK5R1
 MAPK1 recombinant protein  >4 publications with Tau-441 and MAPK1
 MAPK8 recombinant protein  >3 publications with Tau-441 and MAPK8
 CAMK2A recombinant protein  >2 publications with Tau-441 and CAMK2A

Diseases associated with Tau-441 recombinant protein

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >1606 publications with Tau-441 and Nervous System Diseases
 Neurodegenerative Diseases Antibodies  >1488 publications with Tau-441 and Neurodegenerative Diseases
 Brain Diseases Antibodies  >1461 publications with Tau-441 and Brain Diseases
 Dementia Antibodies  >1341 publications with Tau-441 and Dementia
 Tauopathies Antibodies  >1102 publications with Tau-441 and Tauopathies
 Alzheimer Disease Antibodies  >902 publications with Tau-441 and Alzheimer Disease
 Frontotemporal Dementia Antibodies  >508 publications with Tau-441 and Frontotemporal Dementia
 Movement Disorders Antibodies  >364 publications with Tau-441 and Movement Disorders
 Disease Models, Animal Antibodies  >270 publications with Tau-441 and Disease Models, Animal
 Parkinsonian Disorders Antibodies  >266 publications with Tau-441 and Parkinsonian Disorders

Organs/Tissues associated with Tau-441 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1205 publications with Tau-441 and Brain
 Nerve Antibodies  >293 publications with Tau-441 and Nerve
 Vascular Antibodies  >51 publications with Tau-441 and Vascular
 Ganglia Antibodies  >44 publications with Tau-441 and Ganglia
 Muscle Antibodies  >31 publications with Tau-441 and Muscle
 Eye Antibodies  >27 publications with Tau-441 and Eye
 Embryonic Tissue Antibodies  >13 publications with Tau-441 and Embryonic Tissue
 Kidney Antibodies  >7 publications with Tau-441 and Kidney
 Bone Antibodies  >7 publications with Tau-441 and Bone
 Lung Antibodies  >5 publications with Tau-441 and Lung
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