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CD134 Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS520050

PE anti-mouse CD134 monoclonal antibody detects the mouse OX-40 antigen (CD134) which is a member of the tumor necrosis factor (TNF) receptor/nerve growth factor (NGF) receptor superfamily. The OX-40 antigen is the sole receptor for the OX-40 ligand. This… More details

$395 / 0.25 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD134, Monoclonal Antibody
Full Product Name
Anti-Mouse CD134, Purified (Clone OX-86) (rat IgG1)
Product Gene Name
Product Synonym Names
CD134, Purified (Clone OX-86) (rat IgG1); Anti-Mouse CD134 (OX-40 antigen) Monoclonal Antibody
Clonality
Monoclonal
Isotype
Rat IGg1
Clone Number
OX-86
Host
Rat
Species Reactivity
Mouse
Form/Format
Purified
Concentration
1.0mg/ml (lot specific)
Specificity
CD134 (OX-40 Antigen) (Mouse CD134 (OX-40 antigen))
Preparation and Storage
For all formats, store at 4 degree C. DO NOT FREEZE PE conjugates. For long term storage (Purified, Biotin and FITC), aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.
Molecular Weight
29,341 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (1146706..1149703, complement). Location: 1p36
OMIM
600315
3D Structure
ModBase 3D Structure for P43489
Immunogen
Recombinant mouse OX-40 antigen
Donor
Rat AO spleen
Fusion Partner
NS1
Presentation
Purified IgG buffered in PBS and 0.02% NaN3. (Purified from ascitic fluid via Protein G Chromatography). For maximum recovery of contents, spin down tube before use.
Applications Tested/Suitable for anti-CD134 antibody
Immunohistochemistry (IHC)

Testing Data of anti-CD134 antibody

Rat Anti-CD134 Monoclonal Antibody – Cat# MBS520050

Other Notes

Small volumes of anti-CD134 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD134 purchase

MBS520050 is an antibody targeting CD134. Also known as Anti-Mouse CD134, Purified (Clone OX-86) (rat IgG1). Reactive in Mouse. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for CD134. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
CD134 antigen
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily, member 4
NCBI Official Symbol
TNFRSF4
NCBI Official Synonym Symbols
OX40; ACT35; CD134; TXGP1L
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 4
UniProt Synonym Protein Names
ACT35 antigen; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor
UniProt Gene Name
TNFRSF4
UniProt Synonym Gene Names
TXGP1L
UniProt Entry Name
TNR4_HUMAN
NCBI Protein Information
tumor necrosis factor receptor superfamily member 4; OX40 antigen; ACT35 antigen; ATC35 antigen; CD134 antigen; OX40 homologue; OX40L receptor; OX40 cell surface antigen; lymphoid activation antigene ACT35; TAX transcriptionally-activated glycoprotein 1 receptor; tax-transcriptionally activated glycoprotein 1 receptor

NCBI Summary for CD134

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
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UniProt Comments for CD134

Function: Receptor for TNFSF4/OX40L/GP34.

Subunit structure: Interacts with TRAF2, TRAF3 and TRAF5. Ref.7 Ref.8

Subcellular location: Membrane; Single-pass type I membrane protein.

Sequence similarities: Contains 4 TNFR-Cys repeats.

Sequence caution: The sequence AAB33944.1 differs from that shown. Reason: Erroneous initiation.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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