Mouse Anti-CD5 Monoclonal Antibody – Cat# MBS520188

CD5 Antibody – Mouse Monoclonal

Name: CD5 Antibody; Monoclonal; Mouse; Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS520188
Price: 365 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS520188

anti-rat CD5 monoclonal antibody recognizes a determinant expressed on all rat thymocytes and peripheral T lymphocytes. It has been determined that there are 15,000 antigenic sites for MBS520188 per cell on thymocytes and 30,000 on peripheral T cells. This… More details

$365 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CD5, Monoclonal Antibody

Full Product Name

Anti-Rat CD5 PE (Clone OX-19) (mouse IgG1)

Product Gene Name

anti-CD5 antibody

Product Synonym Names

CD5 PE (Clone OX-19) (mouse IgG1); PE Anti-Rat CD5 Monoclonal Antibody

Clonality

Monoclonal

Isotype

Mouse IgG1

Clone Number

OX-19

Host

Mouse

Species Reactivity

Rat

Form/Format

PE (R-PE conjugated Ig buffered in PBS, 0.02% NaN3.and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5mg/ml. (Purified from ascitic fluid via Protein G Chromatography).)

Concentration

Antibody Concentration: 0.1 mg/ml (lot specific)

Specificity

CD5 (Rat CD5)

Preparation and Storage

Store at 4 degree C. DO NOT FREEZE. Avoid prolonged exposure to light.

Molecular Weight

54,578 Da

Chromosome Location

Chromosome: 11; NC_000011.9 (60869930..60895324). Location: 11q13

OMIM

153340

3D Structure

ModBase 3D Structure for P06127

Immunogen

Rat thymocyte glycoproteins, depleted of LC-A, W3/13 antigen and Thy 1.

Fusion Partner

P3-NSI-I-Ag4(NS1/1)

Immunocyte Donor

BALB/c spleen

Presentation

50 ug or 200 ug R-PE labelled Ig buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.

Applications Tested/Suitable for anti-CD5 antibody

Immunohistochemistry (IHC)

Other Notes

Small volumes of anti-CD5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD5 purchase

MBS520188 is an antibody targeting CD5. Also known as Anti-Rat CD5 PE (Clone OX-19) (mouse IgG1). Reactive in Rat. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD5. It may not necessarily be applicable to this product.

NCBI GI #

166197668

NCBI GeneID

921

NCBI Accession #

NP_055022.2

UniProt Primary Accession #

P06127

UniProt Secondary Accession #

A0N0P4; A8K9I3

UniProt Related Accession #

P06127

GenBank Nucleotide #

NM_014207.3

NCBI Official Full Name

T-cell surface glycoprotein CD5

NCBI Official Synonym Full Names

CD5 molecule

NCBI Official Symbol

CD5

NCBI Official Synonym Symbols

T1; LEU1

UniProt Protein Name

T-cell surface glycoprotein CD5

UniProt Synonym Protein Names

Lymphocyte antigen T1/Leu-1

Protein Family

T-cell surface glycoprotein

UniProt Gene Name

CD5

UniProt Synonym Gene Names

LEU1

UniProt Entry Name

CD5_HUMAN

NCBI Protein Information

T-cell surface glycoprotein CD5; CD5 antigen (p56-62); lymphocyte antigen T1/Leu-1

UniProt Comments for CD5

Function: May act as a receptor in regulating T-cell proliferation.

Subunit structure: Interacts with CD72/LYB-2. Interacts with PTPN6/SHP-1

By similarity. Ref.7

Subcellular location: Cell membrane; Single-pass type I membrane protein.

Post-translational modification: Phosphorylated on tyrosine residues by LYN; this creates binding sites for PTPN6/SHP-1

By similarity.

Sequence similarities: Contains 3 SRCR domains.

Research Articles on CD5

1. Our results indicate that CD5(+) B cell subsets might be associated with pathogenesis of SPMS.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CD5 antibody

Products by Pathway	Pathway Diagram
B Cell Receptor Signaling Pathway antibodies	B Cell Receptor Signaling Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram

Diseases associated with anti-CD5 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>2723 publications with CD5 and Neoplasms
Lymphoma Antibodies	>1804 publications with CD5 and Lymphoma
Leukemia, Lymphocytic, Chronic, B-Cell Antibodies	>945 publications with CD5 and Leukemia, Lymphocytic, Chronic, B-Cell
Arthritis, Rheumatoid Antibodies	>172 publications with CD5 and Arthritis, Rheumatoid
Necrosis Antibodies	>168 publications with CD5 and Necrosis
Inflammation Antibodies	>154 publications with CD5 and Inflammation
Anemia Antibodies	>140 publications with CD5 and Anemia
Liver Diseases Antibodies	>120 publications with CD5 and Liver Diseases
Neoplasms, Experimental Antibodies	>114 publications with CD5 and Neoplasms, Experimental
Hyperplasia Antibodies	>91 publications with CD5 and Hyperplasia

Organs/Tissues associated with anti-CD5 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>4022 publications with CD5 and Blood
Spleen Antibodies	>634 publications with CD5 and Spleen
Thymus Antibodies	>471 publications with CD5 and Thymus
Brain Antibodies	>75 publications with CD5 and Brain
Muscle Antibodies	>68 publications with CD5 and Muscle
Heart Antibodies	>51 publications with CD5 and Heart
Connective Tissue Antibodies	>38 publications with CD5 and Connective Tissue
Eye Antibodies	>34 publications with CD5 and Eye
Pancreas Antibodies	>30 publications with CD5 and Pancreas
Uterus Antibodies	>27 publications with CD5 and Uterus