T Cells (Pan) Antibody – Mouse Monoclonal

anti-rat pan T lymphocyte monoclonal antibody immunoprecipitates a two chain structure (95, 120 kDa) largely restricted to T lymphocytes and thymocytes. Applications therefore include the identification of T lymphocyte lineage cells in suspension and tissue. MBS520433 has previously been used to stain T cell areas of the spleen, lymph nodes and Peyer's patch (1). In the thymus, MBS520433 labels all thymocytes, however medullary cells are more strongly positive than cortical cells (1). MBS520433 does not label such non-lymphoid tissues such as brain, kidney, liver and skin (1). This antibody stains approximately 1.0% of bone marrow cells, and 56% thoracic duct lymphocytes. Weak staining occurs with 50% dendritic cells from thoracic duct of mesenteric lymphadenectomized rats. The antigen recognized by MBS520433 is not expressed on granulocytes or macrophages (1). The function of the antigen recognized by this antibody has not, as yet, been associated with any particular function of T cells. MBS520433 does not inhibit the allogeneic mixed leukocyte response, nor does it inhibit T cytotoxic effector cell function.

Small volumes of anti-T cells (pan) antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS520433 is an antibody targeting T cells (pan). Also known as Anti-Rat T cells (pan) FITC (Clone OX-52) (mouse IgG2a). Reactive in Rat. Host: Mouse.