Rat Anti-CD200 Monoclonal Antibody – Cat# MBS520610

CD200 Antibody – Rat Monoclonal

Name: CD200 Antibody; Monoclonal; Rat; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS520610
Price: 325 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS520610

anti-mouse CD200 monoclonal antibody reacts with CD200 (OX2), a highly conserved type I membrane glycoprotein that is expressed on a variety of cell types including thymocytes, some T cells, endothelial and follicular dendritc cells, and brain tissue… More details

$325 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CD200, Monoclonal Antibody

Full Product Name

Anti-Mouse CD200, PE (Clone OX90) (rat IgG2a)

Product Gene Name

anti-CD200 antibody

Product Synonym Names

CD200, PE (Clone OX90) (rat IgG2a); Anti-Mouse CD200 (OX2) Monoclonal Antibody

Clonality

Monoclonal

Isotype

Rat IGg2a

Clone Number

OX90

Host

Rat

Species Reactivity

Mouse

Form/Format

Concentration

Antibody Concentration: 0.1 mg/ml (lot specific)

Specificity

CD200 (Mouse CD200 (OX2))

Preparation and Storage

For all formats, store at 4 degree C. DO NOT FREEZE PE conjugates. For long term storage (Purified, Biotin and FITC), aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.

Molecular Weight

31,264 Da

Chromosome Location

Chromosome: 3; NC_000003.11 (112051194..112081659). Location: 3q13.2

OMIM

155970

3D Structure

ModBase 3D Structure for P41217

Immunogen

mouse CD200-rat CD4 fusion protein

Donor

Rat spleen

Fusion Partner

Y3 myeloma

Presentation

Biotin/FITC/PE conjugated IgG buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.

Other Notes

Small volumes of anti-CD200 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD200 purchase

MBS520610 is an antibody targeting CD200. Also known as Anti-Mouse CD200, PE (Clone OX90) (rat IgG2a). Reactive in Mouse. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for CD200. It may not necessarily be applicable to this product.

NCBI GI #

119600082

NCBI GeneID

4345

NCBI Accession #

EAW79676.1

UniProt Primary Accession #

P41217

UniProt Secondary Accession #

Q6J2Q6; Q6PIQ4; Q8TB85; Q9H3J3; B3KQI1; B4DLW9; D3DN65

UniProt Related Accession #

P41217

NCBI Official Full Name

CD200 antigen, isoform CRA_a

NCBI Official Synonym Full Names

CD200 molecule

NCBI Official Symbol

CD200

NCBI Official Synonym Symbols

MRC; MOX1; MOX2; OX-2

UniProt Protein Name

OX-2 membrane glycoprotein

Protein Family

OX-2 membrane glycoprotein

UniProt Gene Name

CD200

UniProt Synonym Gene Names

MOX1; MOX2

UniProt Entry Name

OX2G_HUMAN

NCBI Protein Information

OX-2 membrane glycoprotein; CD200 antigen; MRC OX-2 antigen; antigen identified by monoclonal antibody MRC OX-2

NCBI Summary for CD200

The protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for CD200

Function: Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.

Subunit structure: Interacts with CD200R1.

Subcellular location: Cell membrane; Single-pass type I membrane protein.

Sequence similarities: Contains 1 Ig-like C2-type (immunoglobulin-like) domain.Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Research Articles on CD200

1. blocking CD200 on tumor cells may have opposite effects on tumor proliferation depending on the "affinity" of the macrophages to form the CD200-CD200R-complex with tumor cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CD200 antibody

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies	Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram

Diseases associated with anti-CD200 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>75 publications with CD200 and Inflammation
Neoplasms Antibodies	>70 publications with CD200 and Neoplasms
Necrosis Antibodies	>36 publications with CD200 and Necrosis
Disease Models, Animal Antibodies	>32 publications with CD200 and Disease Models, Animal
Carcinoma Antibodies	>11 publications with CD200 and Carcinoma
Encephalomyelitis, Autoimmune, Experimental Antibodies	>10 publications with CD200 and Encephalomyelitis, Autoimmune, Experimental
Cardiovascular Diseases Antibodies	>9 publications with CD200 and Cardiovascular Diseases
Breast Neoplasms Antibodies	>8 publications with CD200 and Breast Neoplasms
Fibrosis Antibodies	>5 publications with CD200 and Fibrosis
Embryo Loss Antibodies	>4 publications with CD200 and Embryo Loss

Organs/Tissues associated with anti-CD200 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>143 publications with CD200 and Blood
Brain Antibodies	>65 publications with CD200 and Brain
Skin Antibodies	>59 publications with CD200 and Skin
Bone Marrow Antibodies	>36 publications with CD200 and Bone Marrow
Spleen Antibodies	>28 publications with CD200 and Spleen
Lymph Node Antibodies	>24 publications with CD200 and Lymph Node
Lung Antibodies	>19 publications with CD200 and Lung
Vascular Antibodies	>16 publications with CD200 and Vascular
Embryonic Tissue Antibodies	>13 publications with CD200 and Embryonic Tissue
Eye Antibodies	>12 publications with CD200 and Eye