Rabbit Anti-GLP2R Polyclonal Antibody – Cat# MBS524152

Glucagon-Like Peptide 2 Receptor (GLP2R) Antibody – Rabbit Polyclonal

Name: GLP2R Antibody; Polyclonal; Rabbit; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS524152
Price: 445 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS524152

Glucagon-like peptide 2 (GLP-2) is a 33 aa proglucgon-derived peptide produced by intestinal enteroendocrine cells. It is a potent intestinal growth factor that stimulates crypt cell proliferation and inhibits enterocyte apoptosis in both the small and large… More details

$445 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Glucagon-Like Peptide 2 Receptor (GLP2R), Polyclonal Antibody

Full Product Name

Anti-Mouse Glucagon-Like Peptide 2 Receptor (GLP2R), Purified, (Polyclonal) (Rabbit IgG)

Product Gene Name

anti-GLP2R antibody

Product Synonym Names

Glucagon-Like Peptide 2 Receptor (GLP2R), Purified, (Polyclonal) (Rabbit IgG); Purified Rabbit Anti-Mouse Glucagon-Like Peptide 2 Receptor (GLP2R) Polyclonal Antibody

Clonality

Polyclonal

Isotype

Rabbit IgG

Host

Rabbit

Species Reactivity

Mouse

Form/Format

Purified

Specificity

Glucagon-Like Peptide 2 Receptor (GLP2R) (This antibody is specific for the cytoplasmic domain of Glp2 receptor)

Preparation and Storage

For all formats, store at + 4 degree C. For long term storage, aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.

Molecular Weight

63,001 Da

Chromosome Location

Chromosome: 17; NC_000017.10 (9729152..9794269). Location: 17p13.3

OMIM

603659

3D Structure

ModBase 3D Structure for O95838

Immunogen

20 amino acid synthetic peptide at the C-terminal of Glp2 receptor (493-512aa)

Presentation

100 ug purified IgG buffered in 100 ul PBS and 0.02% NaN3 (1 mg/ml). (Purified from serum via affinity chromatography). For maximum recovery of contents, spin down tube before use.

Applications Tested/Suitable for anti-GLP2R antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-GLP2R antibody

Suggested minimum working dilution of 1:16000 in ELISA and 1:100 in Western Blot. This antibody has not been tested in other application.

Other Notes

Small volumes of anti-GLP2R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GLP2R purchase

MBS524152 is an antibody targeting GLP2R. Also known as Anti-Mouse Glucagon-Like Peptide 2 Receptor (GLP2R), Purified, (Polyclonal) (Rabbit IgG). Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GLP2R. It may not necessarily be applicable to this product.

NCBI GI #

4758438

NCBI GeneID

9340

NCBI Accession #

NP_004237.1

UniProt Primary Accession #

O95838

UniProt Secondary Accession #

Q4VAT3

UniProt Related Accession #

O95838

GenBank Nucleotide #

NM_004246.1

NCBI Official Full Name

glucagon-like peptide 2 receptor

NCBI Official Synonym Full Names

glucagon-like peptide 2 receptor

NCBI Official Symbol

GLP2R

UniProt Protein Name

Glucagon-like peptide 2 receptor

Protein Family

Glucagon-like peptide 2 receptor

UniProt Gene Name

GLP2R

UniProt Synonym Gene Names

GLP-2 receptor; GLP-2-R; GLP-2R

UniProt Entry Name

GLP2R_HUMAN

NCBI Protein Information

glucagon-like peptide 2 receptor; GLP-2R; GLP-2-R; GLP-2 receptor

NCBI Summary for GLP2R

The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R). [provided by RefSeq, Jul 2008]

UniProt Comments for GLP2R

Function: This is a receptor for glucagon-like peptide 2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

Subcellular location: Cell membrane; Multi-pass membrane protein.

Sequence similarities: Belongs to the G-protein coupled receptor 2 family.

Research Articles on GLP2R

1. GLP-2 receptors are highly expressed in gastrointestinal stromal tumors and Crohn's disease.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-GLP2R antibody

Products by Pathway	Pathway Diagram
Class B/2 (Secretin Family Receptors) Pathway antibodies	Class B/2 (Secretin Family Receptors) Pathway Diagram
G Alpha (s) Signalling Events Pathway antibodies	G Alpha (s) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class B Secretin-like Pathway antibodies	GPCRs, Class B Secretin-like Pathway Diagram
Glucagon-type Ligand Receptors Pathway antibodies	Glucagon-type Ligand Receptors Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram

Organs/Tissues associated with anti-GLP2R antibody

Organ/Tissue Name	Pubmed Publications
Intestine Antibodies	>8 publications with GLP2R and Intestine
Brain Antibodies	>2 publications with GLP2R and Brain