• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

XRCC1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5307727

MBS5307727 is an antibody targeting XRCC1. Also known as Mouse monoclonal XRCC1 antibody. Host: Mouse. More details

$1625 / 0.1 mL +2 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
XRCC1, Monoclonal Antibody
Full Product Name
Mouse monoclonal XRCC1 antibody
Product Gene Name
Product Synonym Names
XRCC1 antibody
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2H8
Host
Mouse
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purity/Purification
Purified by affinity chromatography.
Concentration
500 ug-1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
69,477 Da
OMIM
M36089 mRNA
3D Structure
ModBase 3D Structure for P18887
Immunogen
XRCC1 antibody was raised in mouse using a full length recombinant protein of human XRCC1 (NP_006288) produced in HEK293T cells, as the immunogen.
Cross-Reactivity
Human

Product Categories/Family for anti-XRCC1 antibody

Applications Tested/Suitable for anti-XRCC1 antibody
Western Blot (WB)
Application Notes for anti-XRCC1 antibody
WB: 1:500-2000

Western Blot (WB) of anti-XRCC1 antibody

Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant XRCC1 protein (Right) or empty vector (Left) detected with XRCC1 antibody
Mouse Anti-XRCC1 Monoclonal Antibody – Cat# MBS5307727

Other Notes

Small volumes of anti-XRCC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for XRCC1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
XRCC1
NCBI Official Synonym Full Names
X-ray repair cross complementing 1
NCBI Official Symbol
XRCC1
NCBI Official Synonym Symbols
RCC
UniProt Protein Name
DNA repair protein XRCC1
UniProt Synonym Protein Names
X-ray repair cross-complementing protein 1
Protein Family
UniProt Gene Name
XRCC1
NCBI Protein Information
DNA repair protein XRCC1

NCBI Summary for XRCC1

The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for XRCC1

XRCC1: Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. Homodimer. Interacts with polynucleotide kinase (PNK), DNA polymerase-beta (POLB) and DNA ligase III (LIG3). Interacts with APTX and APLF. Interacts with APEX1; the interaction is induced by SIRT1 and increases with the acetylated form of APEX1.

Protein type: DNA repair, damage

Chromosomal Location of Human Ortholog: 19q13.31

Cellular Component: nucleoplasm; nucleus

Molecular Function: DNA ligase activity; enzyme binding; protein binding

Biological Process: base-excision repair; base-excision repair, DNA ligation; double-strand break repair via homologous recombination; nucleotide-excision repair, DNA gap filling; transcription-coupled nucleotide-excision repair
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-XRCC1 antibody

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000