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Substance P (TAC1) Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS530819

MBS530819 is an antibody targeting Tac1. Also known as Substance P antibody. Reactive in To be determined by end-user. Host: Rat. Rat monoclonal Substance P antibody More details

$1670 / 0.5 mL +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Substance P (Tac1), Monoclonal Antibody
Full Product Name
Substance P antibody
Product Gene Name
anti-Tac1 antibody
Product Synonym Names
Monoclonal Substance P; Anti-Substance P
Clonality
Monoclonal
Isotype
IgGa
Clone Number
M09205
Host
Rat
Species Reactivity
To be determined by end-user
Form/Format
Supplied as a lyophilized powder. Reconstitute with 0.5 ml of distilled water.
Preparation and Storage
Store at 4 degree C.
Molecular Weight
11,374 Da
3D Structure
ModBase 3D Structure for P06767
Immunogen
Substance P antibody was raised in rat using substance-P-BSA as the immunogen.

Product Categories/Family for anti-Tac1 antibody

Neuroscience
Applications Tested/Suitable for anti-Tac1 antibody
Immunohistochemistry (IHC)
Application Notes for anti-Tac1 antibody
IHC: 1:200-1:500

Product References and Citations for anti-Tac1 antibody

Effects of extended sidestream smoke exposure on components of the C-fiber axon reflex; Jesse P. Joad, Krishna P. Avadhanam, Katherine C. Watt, Kayleen S. Kott, John M. Bric, Kent E. Pinkerton (Toxicology: Volume: 112 Issue: 3 Page: 195-203 DOI: 10.1016/0300-483X(96)03403-8)
Endocytosis and recycling of neurokinin 1 receptors in enteric neurons; E.F Grady, P.D Gamp, E Jones, P Baluk, D.M McDonald, D.G Payan, N.W Bunnett (Neuroscience: Volume: 75 Issue: 4 Page: 12391254 DOI: 10.1016/0306-4522(96)00357-0)
Perinatal environmental tobacco smoke exposure alters the immune response and airway innervation in infant primates; Mang Yu, Xiaomu Zheng, Janice Peake, Jesse P. Joad, Kent E. Pinkerton (Journal of Allergy and Clinical Immunology: Volume: 122 Issue: 3 Page: 640-647.e1 DOI: 10.1016/j.jaci.2008.04.038)
Labeling of calcitonin gene-related peptide and substance P increases in subnucleus caudalis of rabbit during maxillary sinusitis; A.K Rochea, Ioannis G Koutlasb, K.C Kajander (Brain Research: Volume: 791 Issue: 1-2 Page: 283-289 DOI: 10.1016/S0006-8993(97)01556-4)
Identification of the cholinergic neurons in Guinea-pig sphincter of Oddi ganglia; Erin K Talmage, Kirk Hillsley, Audra L Kennedy, Gary M Mawe (Journal of the Autonomic Nervous System: Volume: 64 Issue: 1 Page: 12-18 DOI: 10.1016/S0165-1838(97)00009-X)

Other Notes

Small volumes of anti-Tac1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Tac1. It may not necessarily be applicable to this product.

NCBI GI #
56068
NCBI GeneID
24806
NCBI Accession #
CAA39752.1
UniProt Primary Accession #
P06767
UniProt Secondary Accession #
P08856; P08857; P22356; Q6LD93
UniProt Related Accession #
P06767
NCBI Official Full Name
substance P
NCBI Official Synonym Full Names
tachykinin, precursor 1
NCBI Official Symbol
Tac1
NCBI Official Synonym Symbols
TAC; PPTA3; Ppt5fl; RATPPTA3
UniProt Protein Name
Protachykinin-1
UniProt Synonym Protein Names
PPT
Protein Family
Protachykinin
UniProt Gene Name
Tac1
UniProt Synonym Gene Names
Nka; Nkna; Tac2; NKA; NPK
UniProt Entry Name
TKN1_RAT
NCBI Protein Information
protachykinin-1

NCBI Summary for Tac1

encodes neuropeptides substance P, neurokinin A, neuropeptide K, and neuropeptide gamma [RGD, Feb 2006]

UniProt Comments for Tac1

Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

Research Articles on Tac1

1. Data demonstrate a role TAC1 in the control energy balance by regulating the levels of adiposity in response to ghrelin administration and to changes in the status of the gonadal function.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Tac1 antibody

 Reference Product  PubMed Publications
 Tacr1 antibody  >33 publications with Tac1 and Tacr1
 Tacr2 antibody  >7 publications with Tac1 and Tacr2
 Tacr3 antibody  >6 publications with Tac1 and Tacr3
 Nts antibody  >3 publications with Tac1 and Nts
 Cck antibody  >1 publications with Tac1 and Cck
 Nps antibody  >1 publications with Tac1 and Nps

Pathways associated with anti-Tac1 antibody

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
 Tachykinin Receptors Bind Tachykinins Pathway antibodies  Tachykinin Receptors Bind Tachykinins Pathway Diagram

Diseases associated with anti-Tac1 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >22 publications with Tac1 and Nervous System Diseases
 Inflammation Antibodies  >22 publications with Tac1 and Inflammation
 Pain Antibodies  >18 publications with Tac1 and Pain
 Disease Models, Animal Antibodies  >14 publications with Tac1 and Disease Models, Animal
 Hyperalgesia Antibodies  >7 publications with Tac1 and Hyperalgesia
 Neurogenic Inflammation Antibodies  >5 publications with Tac1 and Neurogenic Inflammation
 Bipolar Disorder Antibodies  >5 publications with Tac1 and Bipolar Disorder
 Necrosis Antibodies  >5 publications with Tac1 and Necrosis
 Schizophrenia Antibodies  >4 publications with Tac1 and Schizophrenia
 Hypersensitivity Antibodies  >3 publications with Tac1 and Hypersensitivity

Organs/Tissues associated with anti-Tac1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >34 publications with Tac1 and Brain
 Dorsal Root Ganglion Antibodies  >6 publications with Tac1 and Dorsal Root Ganglion
 Pituitary Gland Antibodies  >1 publications with Tac1 and Pituitary Gland
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