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SMAD2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5309620

SMAD2 belongs to the SMAD, a family of proteins similar to the gene products of theDrosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signaltransducers and transcriptional modulators that mediate multiple… More details

$720 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SMAD2, Polyclonal Antibody
Full Product Name
SMAD2 antibody
Product Gene Name
Product Synonym Names
Rabbit polyclonal SMAD2 antibody; Polyclonal SMAD2 antibody; Anti-SMAD2 antibody; SMAD 2 antibody; SMAD-2 antibody; SMAD 2; Mothers against DPP homolog 2 antibody; SMAD2; SMAD-2; MADH2 antibody; Phospho Thr220 antibody; MADR2 antibody; SMAD family member 2 antibody
Clonality
Polyclonal
Host
Rabbit
Form/Format
Liquid form in PBS buffer (no MG2+ or Ca2+), pH 7.4, 150 mm NaCl,0.02% sodium azide and 50% glycerol.
Purity/Purification
Purified by immunoaffinity chromatography.
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage.
Aliquot and store at-20 degree C for long term storage.
Avoid repeated freeze/thaw cycles.
Molecular Weight
48,956 Da
OMIM
601366
Immunogen
SMAD2 antibody was raised in Rabbit using the peptide sequence around phosphorylation site of threonine 220 (P-E-T(p)-P-P) derived from Human Smad2 as the immunogen.
Cross-Reactivity
Human, Mouse, Rat

Product Categories/Family for anti-SMAD2 antibody

Applications Tested/Suitable for anti-SMAD2 antibody
Western Blot (WB)
Application Notes for anti-SMAD2 antibody
WB: 1:500-1:1000

Testing Data of anti-SMAD2 antibody

Western Blot analysis of extracts from Hela cells untreated or treated with PMA using Smad2 (Phospho-Thr220) antibody
Rabbit Anti-SMAD2 Polyclonal Antibody – Cat# MBS5309620

Other Notes

Small volumes of anti-SMAD2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SMAD2 purchase

MBS5309620 is an antibody targeting SMAD2. Also known as SMAD2 antibody. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SMAD2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
NCBI Official Full Name
Smad2
UniProt Protein Name
Mothers against decapentaplegic homolog 2
UniProt Synonym Protein Names
JV18-1; Mad-related protein 2; hMAD-2; SMAD family member 2; SMAD 2; Smad2; hSMAD2
UniProt Gene Name
SMAD2
UniProt Synonym Gene Names
MADH2; MADR2; MAD homolog 2; Mothers against DPP homolog 2; hMAD-2; SMAD 2; Smad2; hSMAD2

UniProt Comments for SMAD2

Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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