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MEK1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5309793

MEK1 is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
MEK1, Polyclonal Antibody
Full Product Name
MEK1 antibody
Product Gene Name
Product Synonym Names
Rabbit polyclonal MEK1 antibody; Polyclonal MEK1 antibody; Anti-MEK1 antibody; MEK-1 antibody; MEK-1; MAP2K1 antibody; MEK1; MKK1 antibody; MEK 1 antibody; Ab 291 antibody; PRKMK1 antibody; MEK 1; MAPKK1 antibody
Clonality
Polyclonal
Host
Rabbit
Form/Format
Liquid form in PBS buffer (no MG2+ or Ca2+), pH 7.4, 150 mm NaCl,0.02% sodium azide and 50% glycerol.
Purity/Purification
Purified by immunoaffinity chromatography.
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage.
Aliquot and store at-20 degree C for long term storage.
Avoid repeated freeze/thaw cycles.
Molecular Weight
34,087 Da
Immunogen
MEK1 antibody was raised in Rabbit using the peptide sequence around aa 289~293 (P-R-T-P-G) derived from Human MEK1 as the immunogen.
Cross-Reactivity
Human, Mouse, Rat

Product Categories/Family for anti-MEK1 antibody

Applications Tested/Suitable for anti-MEK1 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-MEK1 antibody
IHC: 1:50-1:100
WB: 1:500-1:1000

Immunohistochemistry (IHC) of anti-MEK1 antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MEK 1 antibody (left) or the same antibody preincubated with with blocking peptide (right)
Rabbit Anti-MEK1 Polyclonal Antibody – Cat# MBS5309793

Western Blot (WB) of anti-MEK1 antibody

Western Blot analysis of extracts from HepG2 and PC 12 cells using MEK 1 antibody
Rabbit Anti-MEK1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS5309793

Other Notes

Small volumes of anti-MEK1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MEK1 purchase

MBS5309793 is an antibody targeting MEK1. Also known as MEK1 antibody. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MEK1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
MEK1
NCBI Official Symbol
MEK1
NCBI Official Synonym Symbols
ATMEK1; F20B18.180; F20B18_180; MAP kinase/ ERK kinase 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MKK1; NMAPKK
UniProt Protein Name
Mitogen-activated protein kinase kinase 1
UniProt Synonym Protein Names
AtMEK1; NMAPKK
UniProt Gene Name
MKK1
UniProt Synonym Gene Names
MEK1; AtMKK1; MAP kinase kinase 1
NCBI Protein Information
MAP kinase/ ERK kinase 1

NCBI Summary for MEK1

Member of MAP Kinase Kinase. Likely functions in a stress-activated MAPK pathway. Can phosphorylate the MAPK AtMPK4, in response to stress. Gets phosphorylated by MEKK1 in response to wounding.

UniProt Comments for MEK1

MEKK1, MKK1/MKK2 and MPK4/MPK6 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity. Activates by phosphorylation the downstream MPK4. Acts redundantly with MKK2. MKK1-MPK6 module mediates abscisic acid (ABA)-dependent CAT1 expression with H2O2 production and response to drought and salt stress. MKK1-MPK6 module is also involved in sugar signaling during the process of seed germination.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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