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SUCLA2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5312274

Succinyl-CoA synthetase is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SUCLA2, Polyclonal Antibody
Full Product Name
SUCLA2 Antibody
Product Gene Name
Product Synonym Names
Affinity Purified Rabbit Polyclonal SUCLA2 Antibody; Polyclonal SUCLA2 antibody; Anti-SUCLA2 antibody; SUCLA2 antibody; succinyl-CoA synthetase beta-A chain antibody; SUCLA 2 antibody; SUCLA-2; SCS-betaA antibody; SUCLA2; ATP-specific succinyl-CoA synthetase beta subunit antibody; mitochondrial succinyl-CoA ligase [ADP-forming] subunit beta antibody; MTDPS5 antibody; renal carcinoma antigen NY-REN-39 antibody; SUCLA-2 antibody; ATP-specific succinyl-CoA synthetase subunit beta antibody; SUCLA 2; (-)BETA antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Form/Format
Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Purity/Purification
Antigen-Affinity Chromatography
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
50 kDa
OMIM
603921
3D Structure
ModBase 3D Structure for Q9P2R7
Cross-Reactivity
Human, Mouse

Product Categories/Family for anti-SUCLA2 antibody

Applications Tested/Suitable for anti-SUCLA2 antibody
Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-SUCLA2 antibody
IF: 1:100-1:500
IHC-P: 1:100-1:500
ICC: 1:100-1:500
WB: 1:1000-1:20000

Western Blot (WB) of anti-SUCLA2 antibody

Western blot analysis of 20 ug of whole cell lysate (A: mouse brain) using a 10% SDS PAGE gel and SUCLA2 antibody at a dilution of 1:20000
Rabbit Anti-SUCLA2 Polyclonal Antibody – Cat# MBS5312274

Western Blot (WB) of anti-SUCLA2 antibody

Western blot analysis of 30 ug of whole cell lysate (A: Hep G2; B: Molt-4) using a 10% SDS PAGE gel and SUCLA2 antibody at a dilution of 1:1000
Rabbit Anti-SUCLA2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS5312274

Immunofluorescence (IF) of anti-SUCLA2 antibody

Immunofluorescence analysis of methanol-fixed A431, using SUCLA2 antibody at 1:200 dilution.
Rabbit Anti-SUCLA2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS5312274

Immunohistochemistry (IHC) of anti-SUCLA2 antibody

Immunohistochemical staining of paraffin-embedded Cal27 xenograft using SUCLA2 antibody at a dilution of 1:500
Rabbit Anti-SUCLA2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS5312274

Other Notes

Small volumes of anti-SUCLA2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SUCLA2 purchase

MBS5312274 is an antibody targeting SUCLA2. Also known as SUCLA2 Antibody. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SUCLA2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
succinate--CoA ligase
NCBI Official Synonym Full Names
succinate-CoA ligase ADP-forming beta subunit
NCBI Official Symbol
SUCLA2
NCBI Official Synonym Symbols
A-SCS; A-BETA; MTDPS5; SCS-betaA
UniProt Protein Name
Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial
UniProt Synonym Protein Names
ATP-specific succinyl-CoA synthetase subunit beta; Renal carcinoma antigen NY-REN-39; Succinyl-CoA synthetase beta-A chain; SCS-betaA
UniProt Gene Name
SUCLA2
UniProt Synonym Gene Names
SCS-betaA
UniProt Entry Name
SUCB1_HUMAN
NCBI Protein Information
succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

NCBI Summary for SUCLA2

Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6. [provided by RefSeq, Jul 2008]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SUCLA2 antibody

 Reference Product  PubMed Publications
 SUCLG1 antibody  >16 publications with SUCLA2 and SUCLG1
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