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AIMP2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5312793

The JTV1 gene is located on chromosome 7p22 flanked by two genes, HRI and PMS2. JTV1 and HRI overlap slightly and are arranged in a tail-to-tail fashion. JTV1 and PMS2 are separated by approximately 200 base pairs and are arranged head-to-head. JTV1 is… More details

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Product Overview

Online Datasheet in PDF
Product Name
AIMP2, Polyclonal Antibody
Full Product Name
AIMP2 Antibody
Product Gene Name
Product Synonym Names
Affinity Purified Rabbit Polyclonal AIMP2 Antibody; Polyclonal AIMP2 antibody; Anti-AIMP2 antibody; AIMP 2 antibody; JTV-1 antibody; aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 antibody; PRO0992 antibody; AIMP-2; P38 antibody; AIMP-2 antibody; AIMP 2; AIMP2; JTV1 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Form/Format
Lyophilized Form
Purity/Purification
Affinity Chromatography
Preparation and Storage
Store at 4 degree C for short term storage. For long term storage aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles.
OMIM
600859
3D Structure
ModBase 3D Structure for Q13155
Immunogen
AIMP2 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence in the middle region of human AIMP2, different from the related rat and Rabbit sequences by three amino acids, as the immunogen

Product Categories/Family for anti-AIMP2 antibody

Applications Tested/Suitable for anti-AIMP2 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin

Immunohistochemistry (IHC) of anti-AIMP2 antibody

Immunohistochemistry of paraffin-embedded section of Human Rectal Cancer Tissue
Rabbit Anti-AIMP2 Polyclonal Antibody – Cat# MBS5312793

Western Blot (WB) of anti-AIMP2 antibody

Lane 1: Rat Liver Tissue Lysate; Lane 2: Rat Lung Tissue Lysate; Lane 3: Rat Kidney Tissue Lysate, Lane 4: Rat brain Tissue Lysate; Lane 5: Marker; Lane 6: Jurkat Cell Lysate; Lane 7: Cem Cell Lysate; Lane 8: HUT Cell Lysate; Lane 9: U93T Cell Lysate; Lane 10: U93T Cell Lysate
Rabbit Anti-AIMP2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS5312793

Other Notes

Small volumes of anti-AIMP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AIMP2 purchase

MBS5312793 is an antibody targeting AIMP2. Also known as AIMP2 Antibody. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AIMP2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
aminoacyl tRNA synthase complex-interacting multifunctional protein 2 isoform a
NCBI Official Synonym Full Names
aminoacyl tRNA synthetase complex interacting multifunctional protein 2
NCBI Official Symbol
AIMP2
NCBI Official Synonym Symbols
P38; JTV1; HLD17; JTV-1
UniProt Protein Name
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
UniProt Synonym Protein Names
Multisynthase complex auxiliary component p38; Protein JTV-1
UniProt Gene Name
AIMP2
UniProt Synonym Gene Names
JTV1
UniProt Entry Name
AIMP2_HUMAN
NCBI Protein Information
aminoacyl tRNA synthase complex-interacting multifunctional protein 2

NCBI Summary for AIMP2

The protein encoded by this gene is part of the aminoacyl-tRNA synthetase complex, which contains nine different aminoacyl-tRNA synthetases and three non-enzymatic factors. The encoded protein is one of the non-enzymatic factors and is required for assembly and stability of the complex. [provided by RefSeq, May 2016]
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UniProt Comments for AIMP2

JTV1: Required for assembly and stability of the aminoacyl- tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down- regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.

Chromosomal Location of Human Ortholog: 7p22

Cellular Component: membrane; nucleus; cytosol

Molecular Function: protein binding

Biological Process: negative regulation of cell proliferation; tRNA aminoacylation for protein translation; positive regulation of protein ubiquitination; apoptosis; gene expression
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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