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Cofilin (CFL) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5313927

Cofilin regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. More details

$625 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cofilin (CFL), Polyclonal Antibody
Full Product Name
Cofilin Antibody
Product Gene Name
Product Synonym Names
Rabbit Polyclonal Cofilin Antibody; Polyclonal Cofilin antibody; Anti-Cofilin antibody; CFL antibody; CFL1 antibody; COF1 antibody; Cofilin 1 (non-muscle) antibody; Cofilin non-muscle isoform antibody; Cofilin-1 antibody; p18 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Form/Format
Supplied in PBS buffer (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol
Purity/Purification
Affinity Chromatography
Concentration
1 mg/ml (lot specific)
Specificity
Cofilin antibody detects endogenous levels of total Cofilin protein
Preparation and Storage
Store at -20 degree C in small aliquots. Avoid repeat freeze/thaw cycles.
Immunogen
Cofilin antibody was raised in Rabbit using a synthesized non-phosphopeptide derived from human Cofilin around the phosphorylation site of serine 3 (M-A-SP-G-V) as the immunogen.
Cross-Reactivity
Mouse, Rat

Product Categories/Family for anti-CFL antibody

Applications Tested/Suitable for anti-CFL antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CFL antibody
WB: 1:500-1:1000
IHC: 1:50-1:100

Western Blot (WB) of anti-CFL antibody

Western blot analysis of extracts from COLO 205 cells using cofilin antibody and Cofilin antibody (Lanes 3 and 4)
Rabbit Anti-CFL Polyclonal Antibody – Cat# MBS5313927

Immunohistochemistry (IHC) of anti-CFL antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using cofilin antibody
Rabbit Anti-CFL Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS5313927

Other Notes

Small volumes of anti-CFL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CFL purchase

MBS5313927 is an antibody targeting CFL. Also known as Cofilin Antibody. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CFL. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Related Accession #
NCBI Official Full Name
cofilin
NCBI Official Synonym Full Names
cofilin 1
NCBI Official Symbol
CFL1
NCBI Official Synonym Symbols
CFL; cofilin; HEL-S-15
Protein Family
NCBI Protein Information
cofilin-1

NCBI Summary for CFL

The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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