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Patched (PTC) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5314903

Patched is a member of the patched gene family and is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis. This gene functions as a tumor suppressor. More details

$705 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Patched (PTC), Polyclonal Antibody
Full Product Name
Patched Antibody
Product Gene Name
Product Synonym Names
Purified Polyclonal Patched Antibody; Polyclonal Patched antibody; Anti-Patched antibody; PTCH antibody; Protein patched homolog 1 antibody; PTC antibody; PTC1 antibody
Clonality
Polyclonal
Host
Rabbit
Form/Format
Supplied in liquid form in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3 with 30% Glycerol and 0.01% Sodium Azide
Purity/Purification
Immunogen Affinity Chromatography
Specificity
Recognizes endogenous levels of Patched protein
Preparation and Storage
Store at 4 degree C for short term storage. For long term, aliquot and store at -20 degree C. Avoid repeat freeze/thaw cycles.
Immunogen
Patched antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Patched as the immunogen
Cross-Reactivity
Mouse, Rat

Product Categories/Family for anti-PTC antibody

Applications Tested/Suitable for anti-PTC antibody
Western Blot (WB)
Application Notes for anti-PTC antibody
WB: 1:500-1:1000

Western Blot (WB) of anti-PTC antibody

Western blot analysis of Patched expression in HeLa (A); Ramos (B); MCF7 (C); NIH3T3 (D); PC12 (E) whole cell lysates.
Rabbit Anti-PTC Polyclonal Antibody – Cat# MBS5314903

Other Notes

Small volumes of anti-PTC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PTC purchase

MBS5314903 is an antibody targeting PTC. Also known as Patched Antibody. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PTC. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Related Accession #
NCBI Official Full Name
PATCHED
NCBI Official Synonym Full Names
patched 1
NCBI Official Symbol
PTCH1
NCBI Official Synonym Symbols
PTC; BCNS; PTC1; PTCH; NBCCS
Protein Family
NCBI Protein Information
protein patched homolog 1

NCBI Summary for PTC

This gene encodes a member of the patched family of proteins and a component of the hedgehog signaling pathway. Hedgehog signaling is important in embryonic development and tumorigenesis. The encoded protein is the receptor for the secreted hedgehog ligands, which include sonic hedgehog, indian hedgehog and desert hedgehog. Following binding by one of the hedgehog ligands, the encoded protein is trafficked away from the primary cilium, relieving inhibition of the G-protein-coupled receptor smoothened, which results in activation of downstream signaling. Mutations of this gene have been associated with basal cell nevus syndrome and holoprosencephaly. [provided by RefSeq, Aug 2017]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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