• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Nibrin (NBN) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5316214

Nibrin recognizes DNA damage and rapidly relocates to DSB sites and forms nuclear foci. It also has a role in regulation of N/M/R (MRN) protein complex activity which includes end-processing of both physiological and mutagenic DNA double strand breaks (DSBs). More details

$805 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Nibrin (NBN), Polyclonal Antibody
Full Product Name
Nibrin Antibody
Product Gene Name
Product Synonym Names
Purified Polyclonal Nibrin Antibody; Polyclonal Nibrin antibody; Anti-Nibrin antibody; NBS antibody; NBS1 antibody; P95 antibody; Nibrin antibody; Cell cycle regulatory protein p95 antibody; Nijmegen breakage syndrome protein 1 antibody
Clonality
Polyclonal
Host
Rabbit
Form/Format
Supplied in liquid form in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3 with 30% Glycerol and 0.01% Sodium Azide
Purity/Purification
Immunogen Affinity Chromatography
Specificity
Recognizes endogenous levels of Nibrin protein
Preparation and Storage
Store at 4 degree C for short term storage. For long term, aliquot and store at -20 degree C. Avoid repeat freeze/thaw cycles.
Immunogen
Nibrin antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Nibrin (pS343) as the immunogen
Cross-Reactivity
Mouse, Rat

Product Categories/Family for anti-NBN antibody

Applications Tested/Suitable for anti-NBN antibody
Western Blot (WB)
Application Notes for anti-NBN antibody
WB: 1:500-1:1000

Western Blot (WB) of anti-NBN antibody

Western blot analysis of Nibrin (pS343) expression in Jurkat (A); LO2 UV-treated (B); Raw264.7 UV-treated (C); PC12 (D) whole cell lysates.
Rabbit Anti-NBN Polyclonal Antibody – Cat# MBS5316214

Other Notes

Small volumes of anti-NBN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NBN purchase

MBS5316214 is an antibody targeting NBN. Also known as Nibrin Antibody. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NBN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Related Accession #
NCBI Official Full Name
nibrin
NCBI Official Synonym Full Names
nibrin
NCBI Official Symbol
NBN
NCBI Official Synonym Symbols
ATV; NBS; P95; NBS1; AT-V1; AT-V2
Protein Family
NCBI Protein Information
nibrin

NCBI Summary for NBN

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000