Rabbit Anti-NFIA Polyclonal Antibody – Cat# MBS5316421

Western blot analysis of NFIA expression in Jurkat (A); Raw264.7 (B); rat brain (C) whole cell lysates.

NFIA Antibody – Rabbit Polyclonal

Name: NFIA Antibody; Polyclonal; Rabbit; MyBioSource
Brand: MyBioSource
SKU: MBS5316421
Price: 705 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5316421

MBS5316421 is an antibody targeting NFIA. Also known as NFIA Antibody. Host: Rabbit. NFIA is a member of the NF1 (nuclear factor 1) family of transcription factors. More details

$705 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NFIA, Polyclonal Antibody

Full Product Name

NFIA Antibody

Product Gene Name

anti-NFIA antibody

Product Synonym Names

Purified Polyclonal NFIA Antibody; Polyclonal NFIA antibody; Anti-NFIA antibody; NFIA antibody; KIAA1439 antibody; Nuclear factor 1 A-type antibody; NF1-A antibody; Nuclear factor 1/A antibody; CCAAT-box-binding transcription factor antibody; CTF antibody; Nuclear factor I/A antibody; NF-I/A antibody; NFI-A antibody; TGGCA-binding protein antibody; NFIB antibody; Nuclear factor 1 B-type antibody; NF1-B antibody; Nuclear factor 1/B antibody; CCAAT-box-binding transcription factor antibody; CTF antibody; Nuclear factor I/B antibody; NF-I/B antibody; NFI-B antibody; TGGCA-binding protein antibody; NFIC antibody; NFI antibody; Nuclear factor 1 C-type antibody; NF1-C antibody; Nuclear factor 1/C antibody; CCAAT-box-binding transcription factor antibody; CTF antibody; Nuclear factor I/C antibody; NF-I/C antibody; NFI-C antibody; TGGCA-binding protein antibody; NFIX antibody; Nuclear factor 1 X-type antibody; NF1-X antibody; Nuclear factor 1/X antibody; CCAAT-box-binding transcription factor antibody; CTF antibody; Nuclear factor I/X antibody; NF-I/X antibody; NFI-X antibody; TGGCA-binding protein antibody

Clonality

Polyclonal

Host

Rabbit

Form/Format

Supplied in liquid form in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3 with 30% Glycerol and 0.01% Sodium Azide

Purity/Purification

Immunogen Affinity Chromatography

Specificity

Recognizes endogenous levels of NFIA protein

Preparation and Storage

Store at 4 degree C for short term storage. For long term, aliquot and store at -20 degree C. Avoid repeat freeze/thaw cycles.

OMIM

600727

3D Structure

ModBase 3D Structure for Q12857

Immunogen

NFIA antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human NFIA as the immunogen

Cross-Reactivity

Mouse, Rat, Bovine, Chicken, Pig

Product Categories/Family for anti-NFIA antibody

DNA & RNA

Applications Tested/Suitable for anti-NFIA antibody

Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-NFIA antibody

WB: 1:500-1:1000
IHC: 1:100-1:200

Other Notes

Small volumes of anti-NFIA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NFIA. It may not necessarily be applicable to this product.

NCBI GI #

224465184

NCBI GeneID

4774

UniProt Primary Accession #

Q12857

UniProt Related Accession #

Q12857

GenBank Nucleotide #

NP_001138984.1

NCBI Official Full Name

nuclear factor 1 A-type isoform 4

NCBI Official Synonym Full Names

nuclear factor I A

NCBI Official Symbol

NFIA

NCBI Official Synonym Symbols

CTF; NF1-A; NFI-A; NFI-L; BRMUTD; NF-I/A

UniProt Protein Name

Nuclear factor 1 A-type

UniProt Synonym Protein Names

CCAAT-box-binding transcription factor; CTF; Nuclear factor I/A; NF-I/A; NFI-A; TGGCA-binding protein

Protein Family

Nuclear factor

UniProt Gene Name

NFIA

UniProt Synonym Gene Names

KIAA1439; NF1-A; Nuclear factor 1/A; CTF; NF-I/A; NFI-A

UniProt Entry Name

NFIA_HUMAN

NCBI Protein Information

nuclear factor 1 A-type

NCBI Summary for NFIA

This gene encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

UniProt Comments for NFIA

NFI-A: Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. Belongs to the CTF/NF-I family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 1p31.3-p31.2

Cellular Component: nucleoplasm; nucleus; cell junction

Molecular Function: transcription factor binding; transcription factor activity

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; viral genome replication; DNA replication; response to organic cyclic substance

Research Articles on NFIA

1. High NFIA expression in tumors of patients with esophageal squamous cell carcinoma (ESCC) is correlated with lymph node metastasis and poor differentiation. NFIA is found to be an independent predictor of poor prognosis in patients with ESCC.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-NFIA antibody

Products by Pathway	Pathway Diagram
FOXA1 Transcription Factor Network Pathway antibodies	FOXA1 Transcription Factor Network Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway antibodies	RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway Diagram
RNA Polymerase III Abortive And Retractive Initiation Pathway antibodies	RNA Polymerase III Abortive And Retractive Initiation Pathway Diagram
RNA Polymerase III Transcription Pathway antibodies	RNA Polymerase III Transcription Pathway Diagram
RNA Polymerase III Transcription Termination Pathway antibodies	RNA Polymerase III Transcription Termination Pathway Diagram

Diseases associated with anti-NFIA antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>16 publications with NFIA and Nervous System Diseases
Neoplasms Antibodies	>11 publications with NFIA and Neoplasms
Congenital Abnormalities Antibodies	>7 publications with NFIA and Congenital Abnormalities
Nervous System Malformations Antibodies	>6 publications with NFIA and Nervous System Malformations
Disorders of Sex Development Antibodies	>2 publications with NFIA and Disorders of Sex Development
Urogenital Abnormalities Antibodies	>2 publications with NFIA and Urogenital Abnormalities
Disease Models, Animal Antibodies	>1 publications with NFIA and Disease Models, Animal
Kidney Neoplasms Antibodies	>1 publications with NFIA and Kidney Neoplasms
Inflammation Antibodies	>1 publications with NFIA and Inflammation
Learning Disorders Antibodies	>1 publications with NFIA and Learning Disorders

Organs/Tissues associated with anti-NFIA antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>34 publications with NFIA and Brain
Embryonic Tissue Antibodies	>10 publications with NFIA and Embryonic Tissue
Nerve Antibodies	>7 publications with NFIA and Nerve
Lung Antibodies	>6 publications with NFIA and Lung
Thyroid Antibodies	>6 publications with NFIA and Thyroid
Spinal Cord Antibodies	>6 publications with NFIA and Spinal Cord
Blood Antibodies	>6 publications with NFIA and Blood
Liver Antibodies	>6 publications with NFIA and Liver
Bone Antibodies	>6 publications with NFIA and Bone
Kidney Antibodies	>4 publications with NFIA and Kidney