• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

LYVE1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS534019

MBS534019 is an antibody targeting LYVE1. Also known as LYVE1 antibody. Reactive in Human LYVE1. Host: Rabbit. Affinity purified Rabbit polyclonal LYVE1 antibody More details

$625 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LYVE1, Polyclonal Antibody
Full Product Name
LYVE1 antibody
Product Gene Name
anti-LYVE1 antibody
Product Synonym Names
Polyclonal LYVE1; Anti-LYVE1; LYVE-1Lymphatic Vessel Marker; LYVE 1; LYVE -1; Lymphatic Endothelial Cell Marker; LYVE1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human LYVE1
Form/Format
Supplied in lyophilized form in 5 mM PBS buffer pH 7.2, with no preservatives added.
Purity/Purification
LYVE1 antibody was purified by Protein A affinity chromatography.
Specificity
Human LYVE1
Preparation and Storage
Store at -20 degree C until reconstitution. Following reconstitution product may be stored at 4 degree C in the short term. For long term storage aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.
Molecular Weight
35,213 Da
OMIM
605702
3D Structure
ModBase 3D Structure for Q9Y5Y7
Immunogen
LYVE1 antibody was raised in rabbit using recombinant human soluble Lyve-1 as the immunogen.

Product Categories/Family for anti-LYVE1 antibody

Cancer; Purified Polyclonal Antibodies
Applications Tested/Suitable for anti-LYVE1 antibody
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-LYVE1 antibody
FC: 3-10 ug/ml
IF: 6-30 ug/ml
IHC: 6-30 ug/ml
WB: 1-2 ug/ml

Other Notes

Small volumes of anti-LYVE1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LYVE1. It may not necessarily be applicable to this product.

NCBI GI #
40549451
NCBI GeneID
10894
NCBI Accession #
NP_006682
UniProt Primary Accession #
Q9Y5Y7
UniProt Secondary Accession #
Q8TC18; Q9UNF4
UniProt Related Accession #
Q9Y5Y7
GenBank Nucleotide #
NM_006691.3
NCBI Official Full Name
lymphatic vessel endothelial hyaluronic acid receptor 1
NCBI Official Synonym Full Names
lymphatic vessel endothelial hyaluronan receptor 1
NCBI Official Symbol
LYVE1
NCBI Official Synonym Symbols
HAR; XLKD1; LYVE-1; CRSBP-1
UniProt Protein Name
Lymphatic vessel endothelial hyaluronic acid receptor 1
UniProt Synonym Protein Names
Cell surface retention sequence-binding protein 1; CRSBP-1; Extracellular link domain-containing protein 1; Hyaluronic acid receptor
Protein Family
Lymphatic vessel endothelial hyaluronic acid receptor
UniProt Gene Name
LYVE1
UniProt Synonym Gene Names
CRSBP1; HAR; XLKD1; LYVE-1; CRSBP-1
UniProt Entry Name
LYVE1_HUMAN
NCBI Protein Information
lymphatic vessel endothelial hyaluronic acid receptor 1

NCBI Summary for LYVE1

This gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis. [provided by RefSeq, Jul 2008]

UniProt Comments for LYVE1

XLKD1: Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11p15

Cellular Component: membrane; integral to plasma membrane; plasma membrane

Molecular Function: transmembrane receptor activity; hyaluronic acid binding; receptor activity

Biological Process: anatomical structure morphogenesis; glycosaminoglycan metabolic process; transport; cell-matrix adhesion; carbohydrate metabolic process; response to wounding; pathogenesis; cell motility; signal transduction; hyaluronan metabolic process; hyaluronan catabolic process
Show more

Research Articles on LYVE1

1. High LYVE expression is associated with visceral pleural invasion and lymphatic thromboembolism in non-small-cell lung cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LYVE1 antibody

 Reference Product  PubMed Publications
 CD44 antibody  >20 publications with LYVE1 and CD44
 FGF2 antibody  >3 publications with LYVE1 and FGF2
 STAB2 antibody  >3 publications with LYVE1 and STAB2
 FIGF antibody  >1 publications with LYVE1 and FIGF
 ATM antibody  >1 publications with LYVE1 and ATM

Pathways associated with anti-LYVE1 antibody

 Products by Pathway  Pathway Diagram
 Glycosaminoglycan Metabolism Pathway antibodies  Glycosaminoglycan Metabolism Pathway Diagram
 Hyaluronan Metabolism Pathway antibodies  Hyaluronan Metabolism Pathway Diagram
 Hyaluronan Uptake And Degradation Pathway antibodies  Hyaluronan Uptake And Degradation Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Carbohydrates Pathway antibodies  Metabolism Of Carbohydrates Pathway Diagram

Diseases associated with anti-LYVE1 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >22 publications with LYVE1 and Inflammation
 Disease Models, Animal Antibodies  >14 publications with LYVE1 and Disease Models, Animal
 Neoplasms, Experimental Antibodies  >13 publications with LYVE1 and Neoplasms, Experimental
 Lung Diseases Antibodies  >12 publications with LYVE1 and Lung Diseases
 Necrosis Antibodies  >12 publications with LYVE1 and Necrosis
 Liver Neoplasms Antibodies  >10 publications with LYVE1 and Liver Neoplasms
 Edema Antibodies  >9 publications with LYVE1 and Edema
 Liver Diseases Antibodies  >9 publications with LYVE1 and Liver Diseases
 Uterine Cervical Neoplasms Antibodies  >7 publications with LYVE1 and Uterine Cervical Neoplasms
 Fibrosis Antibodies  >5 publications with LYVE1 and Fibrosis

Organs/Tissues associated with anti-LYVE1 antibody

 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >186 publications with LYVE1 and Vascular
 Eye Antibodies  >23 publications with LYVE1 and Eye
 Lung Antibodies  >22 publications with LYVE1 and Lung
 Muscle Antibodies  >17 publications with LYVE1 and Muscle
 Embryonic Tissue Antibodies  >16 publications with LYVE1 and Embryonic Tissue
 Liver Antibodies  >15 publications with LYVE1 and Liver
 Bone Antibodies  >11 publications with LYVE1 and Bone
 Stomach Antibodies  >10 publications with LYVE1 and Stomach
 Connective Tissue Antibodies  >9 publications with LYVE1 and Connective Tissue
 Heart Antibodies  >7 publications with LYVE1 and Heart
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000