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OXTR Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS535669

MBS535669 is an antibody targeting OXTR. Also known as OXTR antibody. Reactive in Human. Host: Rabbit. Rabbit polyclonal OXTR antibody More details

$1660 / 0.05 mg +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
OXTR, Polyclonal Antibody
Full Product Name
OXTR antibody
Product Gene Name
anti-OXTR antibody
Product Synonym Names
Polyclonal OXTR; Anti-OXTR; oxtr; oxytocin receptor; Oxt-r
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1% NaN3.
Purity/Purification
OXTR antibody was purified by affinity chromatography.
Concentration
1.0 mg/ml (lot specific)
Specificity
Human
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -70 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
42,772 Da
OMIM
167055
3D Structure
ModBase 3D Structure for P30559
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.
Immunogen
OXTR antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.

Product Categories/Family for anti-OXTR antibody

Signal Transduction
Applications Tested/Suitable for anti-OXTR antibody
Immunohistochemistry (IHC) Paraffin
Application Notes for anti-OXTR antibody
IHC-P: 20 ug/ml

Other Notes

Small volumes of anti-OXTR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for OXTR. It may not necessarily be applicable to this product.

NCBI GI #
32307152
NCBI GeneID
5021
NCBI Accession #
NP_000907.2
UniProt Primary Accession #
P30559
UniProt Secondary Accession #
Q15071
UniProt Related Accession #
P30559
GenBank Nucleotide #
NM_000916.3
NCBI Official Full Name
oxytocin receptor
NCBI Official Synonym Full Names
oxytocin receptor
NCBI Official Symbol
OXTR
NCBI Official Synonym Symbols
OT-R
UniProt Protein Name
Oxytocin receptor
Protein Family
Oxytocin receptor
UniProt Gene Name
OXTR
UniProt Synonym Gene Names
OT-R
UniProt Entry Name
OXYR_HUMAN
NCBI Protein Information
oxytocin receptor

NCBI Summary for OXTR

The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. [provided by RefSeq, Jul 2008]
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UniProt Comments for OXTR

OXTR: Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol- calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.

Protein type: Receptor, GPCR; Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 3p25

Cellular Component: microvillus; cell-cell adherens junction; integral to plasma membrane; apical plasma membrane; plasma membrane

Molecular Function: oxytocin receptor activity; peptide hormone binding; peptide binding; vasopressin receptor activity

Biological Process: lactation; response to peptide hormone stimulus; response to anoxia; heart development; female pregnancy; positive regulation of synaptic transmission, glutamatergic; response to estradiol stimulus; elevation of cytosolic calcium ion concentration; cell surface receptor linked signal transduction; muscle contraction; response to drug; eating behavior; maternal behavior; response to amphetamine; positive regulation of synaptic transmission, GABAergic; social behavior; response to cocaine; sleep; memory; cellular response to hormone stimulus; G-protein coupled receptor protein signaling pathway; positive regulation of synaptogenesis; telencephalon development; regulation of systemic arterial blood pressure by vasopressin; gut development; suckling behavior; response to cytokine stimulus; maternal process involved in parturition; positive regulation of vasoconstriction; sperm ejaculation; response to progesterone stimulus; positive regulation of blood pressure
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Research Articles on OXTR

1. Carriers of both the T allele of OXTR rs1042778 and the C allele of clock rs1801260 showed the lowest total prosocial tendency scores compared with the other groups. the clock gene and OXT/AVP systems are intertwined and contribute to human prosociality.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-OXTR antibody

 Reference Product  PubMed Publications
 OXT antibody  >66 publications with OXTR and OXT
 AVP antibody  >14 publications with OXTR and AVP
 PTGFR antibody  >2 publications with OXTR and PTGFR
 NPS antibody  >2 publications with OXTR and NPS

Pathways associated with anti-OXTR antibody

 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Myometrial Relaxation And Contraction Pathways antibodies  Myometrial Relaxation And Contraction Pathways Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram

Diseases associated with anti-OXTR antibody

 Disease Name  Pubmed Publications
 Child Development Disorders, Pervasive Antibodies  >37 publications with OXTR and Child Development Disorders, Pervasive
 Autistic Disorder Antibodies  >30 publications with OXTR and Autistic Disorder
 Cognition Disorders Antibodies  >19 publications with OXTR and Cognition Disorders
 Schizophrenia Antibodies  >12 publications with OXTR and Schizophrenia
 Depressive Disorder Antibodies  >9 publications with OXTR and Depressive Disorder
 Inflammation Antibodies  >8 publications with OXTR and Inflammation
 Premature Birth Antibodies  >8 publications with OXTR and Premature Birth
 Pain Antibodies  >5 publications with OXTR and Pain
 Necrosis Antibodies  >3 publications with OXTR and Necrosis
 Brain Diseases Antibodies  >2 publications with OXTR and Brain Diseases

Organs/Tissues associated with anti-OXTR antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >120 publications with OXTR and Brain
 Uterus Antibodies  >29 publications with OXTR and Uterus
 Embryonic Tissue Antibodies  >6 publications with OXTR and Embryonic Tissue
 Heart Antibodies  >6 publications with OXTR and Heart
 Connective Tissue Antibodies  >6 publications with OXTR and Connective Tissue
 Ovary Antibodies  >4 publications with OXTR and Ovary
 Liver Antibodies  >4 publications with OXTR and Liver
 Lung Antibodies  >2 publications with OXTR and Lung
 Kidney Antibodies  >2 publications with OXTR and Kidney
 Skin Antibodies  >2 publications with OXTR and Skin
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