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CNPase Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS536204

MBS536204 is an antibody targeting CNPase. Also known as CNPase antibody. Reactive in Human. Host: Rabbit. Affinity purified Rabbit polyclonal CNPase antibody More details

$710 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CNPase, Polyclonal Antibody
Full Product Name
CNPase antibody
Product Gene Name
anti-CNPase antibody
Product Synonym Names
Polyclonal CNPase; Anti-CNPase; 2'; 3'-cyclic Nucleotide 3'-Phosphodiesterase
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Affinity purified and supplied in PBS, with 0.02% NaN3.
Purity/Purification
CNPase antibody was purified by affinity chromatography.
Concentration
1.0 mg/ml (lot specific)
Specificity
Human
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
45,099 Da
OMIM
123830
3D Structure
ModBase 3D Structure for P09543
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Immunogen
CNPase antibody was raised in rabbit using residues 68-84 [RVIVDKYRDGTKMVSAD] of the 46-48 kDa human CNPase protein as the immunogen.

Product Categories/Family for anti-CNPase antibody

Neuroscience; Purified Polyclonal Antibodies
Applications Tested/Suitable for anti-CNPase antibody
Western Blot (WB)
Application Notes for anti-CNPase antibody
WB: 1:500-1:1,000

Other Notes

Small volumes of anti-CNPase antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CNPase. It may not necessarily be applicable to this product.

NCBI GI #
94721261
NCBI GeneID
1267
NCBI Accession #
NP_149124.3
UniProt Primary Accession #
P09543
UniProt Related Accession #
P09543
GenBank Nucleotide #
NM_033133.4
NCBI Official Full Name
2',3'-cyclic-nucleotide 3'-phosphodiesterase
NCBI Official Synonym Full Names
2',3'-cyclic nucleotide 3' phosphodiesterase
NCBI Official Symbol
CNP
NCBI Official Synonym Symbols
CNP1
UniProt Protein Name
2',3'-cyclic-nucleotide 3'-phosphodiesterase
Protein Family
2',3'-cyclic-nucleotide 3'-phosphodiesterase
UniProt Gene Name
CNP
UniProt Synonym Gene Names
CNP; CNPase
UniProt Entry Name
CN37_HUMAN
NCBI Protein Information
2',3'-cyclic-nucleotide 3'-phosphodiesterase

UniProt Comments for CNPase

CNP: May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. Exists as monomers and homodimers. Belongs to the cyclic nucleotide phosphodiesterase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.4.37; Phosphodiesterase; Cell development/differentiation

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: extracellular space; microtubule; microvillus; pseudopodium; nucleoplasm; mitochondrial outer membrane; membrane; perinuclear region of cytoplasm; mitochondrial inner membrane; cytoplasm; plasma membrane; melanosome; nucleus

Molecular Function: cyclic nucleotide binding; RNA binding; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity

Biological Process: synaptic transmission; substantia nigra development; axonogenesis; adult locomotory behavior; response to toxin; forebrain development; oligodendrocyte differentiation; response to lipopolysaccharide; microtubule cytoskeleton organization and biogenesis; regulation of mitochondrial membrane permeability; cyclic nucleotide catabolic process; aging
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Research Articles on CNPase

1. kidneys express 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase), and renal CNPase mediates in part the renal 2',3'-cAMP-adenosine pathway

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CNPase antibody

 Products by Pathway  Pathway Diagram
 Glial Cell Differentiation Pathway antibodies  Glial Cell Differentiation Pathway Diagram

Diseases associated with anti-CNPase antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >254 publications with CNPase and Nervous System Diseases
 Brain Diseases Antibodies  >192 publications with CNPase and Brain Diseases
 Disease Models, Animal Antibodies  >100 publications with CNPase and Disease Models, Animal
 Inflammation Antibodies  >73 publications with CNPase and Inflammation
 Kidney Diseases Antibodies  >54 publications with CNPase and Kidney Diseases
 Hypertrophy Antibodies  >43 publications with CNPase and Hypertrophy
 Fibrosis Antibodies  >42 publications with CNPase and Fibrosis
 Necrosis Antibodies  >39 publications with CNPase and Necrosis
 Liver Diseases Antibodies  >26 publications with CNPase and Liver Diseases
 Hemorrhage Antibodies  >18 publications with CNPase and Hemorrhage

Organs/Tissues associated with anti-CNPase antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >908 publications with CNPase and Brain
 Blood Antibodies  >542 publications with CNPase and Blood
 Nerve Antibodies  >485 publications with CNPase and Nerve
 Vascular Antibodies  >361 publications with CNPase and Vascular
 Heart Antibodies  >334 publications with CNPase and Heart
 Muscle Antibodies  >316 publications with CNPase and Muscle
 Kidney Antibodies  >185 publications with CNPase and Kidney
 Bone Antibodies  >126 publications with CNPase and Bone
 Spinal Cord Antibodies  >115 publications with CNPase and Spinal Cord
 Lung Antibodies  >95 publications with CNPase and Lung
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