Rabbit Anti-ALKBH1 Polyclonal Antibody – Cat# MBS536459

Western Blot showing ALKBH1 antibody used at a concentration of 1 ug/ml against Fetal Kidney Lysate

ALKBH1 Antibody – Rabbit Polyclonal

Name: ALKBH1 Antibody; Polyclonal; Rabbit; MyBioSource
Brand: MyBioSource
SKU: MBS536459
Price: 1110 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS536459

MBS536459 is an antibody targeting ALKBH1. Also known as ALKBH1 antibody. Host: Rabbit. Affinity purified rabbit polyclonal ALKBH1 antibody More details

$1110 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ALKBH1, Polyclonal Antibody

Full Product Name

ALKBH1 antibody

Product Gene Name

anti-ALKBH1 antibody

Product Synonym Names

Polyclonal ALKBH1; Anti-ALKBH1; ALKBH 1; alkB; E Coli; ALKBH1; ALKBH-1; ALKBH; alkylation repair homolog 1; ABH; hABH; ABH1

Clonality

Polyclonal

Host

Rabbit

Form/Format

Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.

Concentration

1 mg/ml (lot specific)

Preparation and Storage

Store at 4 degree C, following reconstitution, aliquot and store at -20 degree C. Avoid repeated freeze-thaw cycles.

Molecular Weight

43,832 Da

OMIM

605345

3D Structure

ModBase 3D Structure for Q13686

Cross-Reactivity

Human

Immunogen

ALKBH1 antibody was raised in rabbit using the N terminal of ALKBH1 as the immunogen

Product Categories/Family for anti-ALKBH1 antibody

Infectious Disease; Purified Polyclonal Antibodies

Applications Tested/Suitable for anti-ALKBH1 antibody

Western Blot (WB)

Application Notes for anti-ALKBH1 antibody

Optimal conditions to be determined by the end user

Other Notes

Small volumes of anti-ALKBH1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ALKBH1. It may not necessarily be applicable to this product.

NCBI GI #

87298840

NCBI GeneID

8846

NCBI Accession #

NP_006011.2

UniProt Primary Accession #

Q13686

UniProt Secondary Accession #

Q8TAU1; Q9ULA7

UniProt Related Accession #

Q13686

GenBank Nucleotide #

NM_006020.2

NCBI Official Full Name

alkylated DNA repair protein alkB homolog 1

NCBI Official Synonym Full Names

alkB homolog 1, histone H2A dioxygenase

NCBI Official Symbol

ALKBH1

NCBI Official Synonym Symbols

ABH; ABH1; alkB; hABH; ALKBH

UniProt Protein Name

Alkylated DNA repair protein alkB homolog 1

UniProt Synonym Protein Names

Alpha-ketoglutarate-dependent dioxygenase ABH1; DNA lyase ABH1 (EC:4.2.99.18); DNA oxidative demethylase ALKBH1

Protein Family

DNA demethylase

UniProt Gene Name

ALKBH1

UniProt Synonym Gene Names

ABH; ABH1; ALKBH

UniProt Entry Name

ALKB1_HUMAN

NCBI Protein Information

alkylated DNA repair protein alkB homolog 1

NCBI Summary for ALKBH1

This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. [provided by RefSeq, Jul 2008]

UniProt Comments for ALKBH1

ALKBH: Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation. Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites. DNA lyase activity does not require alpha-ketoglutarate and iron. Belongs to the alkB family.

Protein type: EC 4.2.99.18; EC 1.14.11.33; DNA repair, damage

Chromosomal Location of Human Ortholog: 14q24.3

Cellular Component: mitochondrion

Molecular Function: DNA-(apurinic or apyrimidinic site) lyase activity; ferrous iron binding; chemoattractant activity

Biological Process: developmental growth; DNA dealkylation; positive chemotaxis; in utero embryonic development; RNA repair; neuron migration; negative regulation of neuron apoptosis; DNA repair; DNA catabolic process, endonucleolytic; neurite development; placenta development

Research Articles on ALKBH1

1. ALKBH1's role in class switch recombination and abasic site cleavage during base excision repair

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ALKBH1 antibody

Reference Product	PubMed Publications
ALKBH3 antibody	>6 publications with ALKBH1 and ALKBH3
ALKBH2 antibody	>4 publications with ALKBH1 and ALKBH2
ALKBH8 antibody	>4 publications with ALKBH1 and ALKBH8
ALKBH7 antibody	>2 publications with ALKBH1 and ALKBH7
ALKBH4 antibody	>1 publications with ALKBH1 and ALKBH4

Pathways associated with anti-ALKBH1 antibody

Products by Pathway	Pathway Diagram
Integrated Breast Cancer Pathway antibodies	Integrated Breast Cancer Pathway Diagram

Diseases associated with anti-ALKBH1 antibody

Disease Name	Pubmed Publications
Craniofacial Abnormalities Antibodies	>1 publications with ALKBH1 and Craniofacial Abnormalities
Neoplasms, Experimental Antibodies	>1 publications with ALKBH1 and Neoplasms, Experimental
Inflammation Antibodies	>1 publications with ALKBH1 and Inflammation

Organs/Tissues associated with anti-ALKBH1 antibody

Organ/Tissue Name	Pubmed Publications
Testis Antibodies	>3 publications with ALKBH1 and Testis
Lung Antibodies	>3 publications with ALKBH1 and Lung
Bone Antibodies	>2 publications with ALKBH1 and Bone
Placenta Antibodies	>1 publications with ALKBH1 and Placenta
Eye Antibodies	>1 publications with ALKBH1 and Eye
Blood Antibodies	>1 publications with ALKBH1 and Blood
Connective Tissue Antibodies	>1 publications with ALKBH1 and Connective Tissue
Skin Antibodies	>1 publications with ALKBH1 and Skin
Embryonic Tissue Antibodies	>1 publications with ALKBH1 and Embryonic Tissue