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MYPN Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS536477

MBS536477 is an antibody targeting MYPN. Also known as MYPN antibody. Host: Rabbit. Affinity purified rabbit polyclonal MYPN antibody More details

$1120 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MYPN, Polyclonal Antibody
Full Product Name
MYPN antibody
Product Gene Name
Product Synonym Names
Polyclonal MYPN; Anti-MYPN; myopalladin; MYOP
Clonality
Polyclonal
Host
Rabbit
Form/Format
Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C, following reconstitution, aliquot and store at -20 degree C. Avoid repeated freeze-thaw cycles.
Molecular Weight
56,185 Da
OMIM
608517
3D Structure
ModBase 3D Structure for Q86TC9
Cross-Reactivity
Human
Immunogen
MYPN antibody was raised in rabbit using the C terminal of MYPN as the immunogen
Applications Tested/Suitable for anti-MYPN antibody
Western Blot (WB)
Application Notes for anti-MYPN antibody
Optimal conditions to be determined by the end user

Western Blot (WB) of anti-MYPN antibody

Western Blot showing MYPN antibody used at a concentration of 1.0 ug/ml against HepG2 Cell Lysate
Rabbit Anti-MYPN Polyclonal Antibody – Cat# MBS536477

Other Notes

Small volumes of anti-MYPN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MYPN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
myopalladin isoform b
NCBI Official Synonym Full Names
myopalladin
NCBI Official Symbol
MYPN
NCBI Official Synonym Symbols
MYOP; RCM4; CMH22; CMD1DD
UniProt Protein Name
Myopalladin
UniProt Synonym Protein Names
145 kDa sarcomeric protein
Protein Family
UniProt Gene Name
MYPN
UniProt Synonym Gene Names
MYOP
UniProt Entry Name
MYPN_HUMAN
NCBI Protein Information
myopalladin

NCBI Summary for MYPN

Striated muscle in vertebrates comprises large proteins which must be organized properly to contract efficiently. Z-lines in striated muscle are a sign of this organization, representing the ends of actin thin filaments, titin, nebulin or nebulette and accessory proteins required for structure and function. This gene encodes a protein which interacts with nebulin in skeletal muscle or nebulette in cardiac muscle and alpha-actinin. In addition, this gene product can interact with a protein with the I-band indicating it has a regulatory as well as structural function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
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UniProt Comments for MYPN

MYPN: Component of the sarcomere that tethers together nebulin (skeletal muscle) and nebulette (cardiac muscle) to alpha-actinin, at the Z lines. Belongs to the myotilin/palladin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Actin-binding

Chromosomal Location of Human Ortholog: 10q21.3

Cellular Component: I band; nucleus; Z disc

Molecular Function: protein binding; cytoskeletal protein binding; actin binding; muscle alpha-actinin binding; SH3 domain binding

Biological Process: sarcomere organization

Disease: Cardiomyopathy, Dilated, 1kk
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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