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FGF16 Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS536556

MBS536556 is an active protein targeting FGF16. Also known as FGF16 protein. Host: Human. Purified recombinant Human FGF16 protein More details

$435 / 0.005 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FGF16, Active Protein
Full Product Name
FGF16 protein
Product Gene Name
FGF16 active protein
Product Synonym Names
FGF 16 protein; FGF 16; FGF-16 protein; FGF16; FGF-16; Fibroblast Growth Factor-16 protein; FGFG protein
Sequence
Region of FGF16 protein correspond ing to amino acids MAEVGGVFAS LDWDLHGFSS SLGNVPLADS PGFLNERLGQ IEGKLQRGSP TDFAHLKGIL RRRQLYCRTG FHLEIFPNGT VHGTRHDHSR FGILEFISLA VGLISIRGVD SGLYLGMNER GELYGSKKLT RECVFREQFE ENWYNTYAST LYKHSDSERQ YYVALNKDGS PREGYRTKRH QKFTHFLPRP VDPSKLPSMS RDLFHYR.
Host
Human
Form/Format
Supplied as a lyophilized powder.
Purity/Purification
> 95% pure
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
23.7 kDa
OMIM
300827
3D Structure
ModBase 3D Structure for O43320
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Protein Type
Recombinant
Bioactivity
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is approximately 0.5 ng/ml, corresponding to a specific activity of approximately 2 x 10^6 units/mg.
Endotoxin Levels
Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Expression System
E Coli

Product Categories/Family for FGF16 active protein

Cytokines & Growth Factors
Applications Tested/Suitable for FGF16 active protein
User optimized

Other Notes

Small volumes of FGF16 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FGF16. It may not necessarily be applicable to this product.

NCBI GI #
4503691
NCBI GeneID
8823
NCBI Accession #
NP_003859.1
UniProt Primary Accession #
O43320
UniProt Related Accession #
O43320
GenBank Nucleotide #
NM_003868.1
NCBI Official Full Name
fibroblast growth factor 16
NCBI Official Synonym Full Names
fibroblast growth factor 16
NCBI Official Symbol
FGF16
NCBI Official Synonym Symbols
MF4; FGF-16
UniProt Protein Name
Fibroblast growth factor 16
Protein Family
Fibroblast growth factor
UniProt Gene Name
FGF16
UniProt Synonym Gene Names
FGF-16
UniProt Entry Name
FGF16_HUMAN
NCBI Protein Information
fibroblast growth factor 16

NCBI Summary for FGF16

This gene encodes a member of a family of proteins that are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene is expressed in cardiac cells and is required for proper heart development. Mutation in this gene was also observed in individuals with metacarpal 4-5 fusion. [provided by RefSeq, Mar 2014]
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UniProt Comments for FGF16

FGF16: Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation, and is required for normal cardiomyocyte proliferation and heart development. Belongs to the heparin-binding growth factors family.

Protein type: Cytokine

Chromosomal Location of Human Ortholog: Xq13

Cellular Component: extracellular space; extracellular region

Molecular Function: growth factor activity; fibroblast growth factor receptor binding

Biological Process: epidermal growth factor receptor signaling pathway; regulation of endothelial cell proliferation; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; nerve growth factor receptor signaling pathway; metabolic process; signal transduction; response to temperature stimulus; organ morphogenesis; cell-cell signaling; regulation of MAP kinase activity; insulin receptor signaling pathway; innate immune response

Disease: Metacarpal 4-5 Fusion
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Research Articles on FGF16

1. Identification of an FGF16 mutation in metacarpal 4-5 fusion.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with FGF16 active protein

 Products by Pathway  Pathway Diagram
 Activated Point Mutants Of FGFR2 Pathway antibodies  Activated Point Mutants Of FGFR2 Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Constitutive Signaling By Aberrant PI3K In Cancer Pathway antibodies  Constitutive Signaling By Aberrant PI3K In Cancer Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Diseases Of Signal Transduction Pathway antibodies  Diseases Of Signal Transduction Pathway Diagram
 Downstream Signal Transduction Pathway antibodies  Downstream Signal Transduction Pathway Diagram
 Downstream Signaling Events Of B Cell Receptor (BCR) Pathway antibodies  Downstream Signaling Events Of B Cell Receptor (BCR) Pathway Diagram
 Downstream Signaling Of Activated FGFR1 Pathway antibodies  Downstream Signaling Of Activated FGFR1 Pathway Diagram

Diseases associated with FGF16 active protein

 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >4 publications with FGF16 and Heart Diseases
 Hypertrophy Antibodies  >3 publications with FGF16 and Hypertrophy
 Ovarian Neoplasms Antibodies  >2 publications with FGF16 and Ovarian Neoplasms
 Carcinoma Antibodies  >2 publications with FGF16 and Carcinoma
 Hemorrhage Antibodies  >1 publications with FGF16 and Hemorrhage
 Lung Neoplasms Antibodies  >1 publications with FGF16 and Lung Neoplasms
 Cardiomegaly Antibodies  >1 publications with FGF16 and Cardiomegaly
 Hyperglycemia Antibodies  >1 publications with FGF16 and Hyperglycemia
 Heart Failure Antibodies  >1 publications with FGF16 and Heart Failure
 Weight Loss Antibodies  >1 publications with FGF16 and Weight Loss
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