Figure annotation denotes ug of protein loaded and % gel used.

LAIR1 Recombinant Protein

Name: LAIR1 Recombinant Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS536719
Price: 965 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS536719

MBS536719 is a recombinant protein targeting LAIR1. Also known as LAIR1 protein. Host: Human. Purified recombinant Human LAIR1 protein More details

$965 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LAIR1, Recombinant Protein

Full Product Name

LAIR1 protein

Product Gene Name

LAIR1 recombinant protein

Product Synonym Names

D7Bwg0421e protein; Leukocyte-associated immunoglobulin-like receptor 1 protein; LAIR 1 protein; LAIR-1; LAIR1 protein protein; Lair1 protein; CD305 protein; LAIR-1 (Extracellular domain) protein; Leukocyte associated Ig like receptor 1 protein; Leukocyte-associated immunoglobulin-like receptor 1 isoform a 5133400O11Rik protein; LAIR-1 protein; CD305 protein protein; LAIR1; LAIR 1; mLAIR1 protein; Leukocyte associated immunoglobulin like receptor 1 protein

Sequence

Extracellu lar domain;22- 125 amino acids: MQEEDLPRPS ISAEPGTVIP LGSHVTFVCR GPVGVQTFRL ERESRSTYND TEDVSQASPS ESEARFRIDS VSEGNAGPYR CIYYKPPKWS EQSDYLELLV KETSG

Host

Human

Form/Format

Supplied as a liquid in 20mM Tris-HCl, pH7.5, containing 50mM NaCl, and 1mM EDTA.

Purity/Purification

> 95% pure

Concentration

1 mg/ml (lot specific)

Preparation and Storage

Store at 4 degree C for short term storage (1/2 weeks). Aliquot and store at -20 degree C or - 70 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Molecular Weight

11.7 kDa (105 aa), confirmed by MALDI-TOF.

OMIM

602992

3D Structure

ModBase 3D Structure for Q6GTX8

Protein Type

Recombinant

Expression System

E Coli

Product Categories/Family for LAIR1 recombinant protein

Immunology

Applications Tested/Suitable for LAIR1 recombinant protein

SDS-PAGE

Other Notes

Small volumes of LAIR1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LAIR1. It may not necessarily be applicable to this product.

NCBI GI #

49457055

NCBI Accession #

CAG46848.1

UniProt Primary Accession #

Q6GTX8

NCBI Official Full Name

LAIR1, partial

UniProt Protein Name

Leukocyte-associated immunoglobulin-like receptor 1

UniProt Synonym Protein Names

CD_antigen: CD305

Protein Family

Leukocyte-associated immunoglobulin-like receptor

UniProt Gene Name

LAIR1

UniProt Synonym Gene Names

CD305; LAIR-1; hLAIR1

UniProt Entry Name

LAIR1_HUMAN

NCBI Summary for LAIR1

The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

UniProt Comments for LAIR1

LAIR-1: an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region called the leukocyte receptor cluster, which contains at least 25 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 19q13.4

Cellular Component: integral to membrane; plasma membrane

Molecular Function: protein binding

Biological Process: immune system process

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with LAIR1 recombinant protein

Disease Name	Pubmed Publications
Chromosome Aberrations Antibodies	>2 publications with LAIR1 and Chromosome Aberrations
Inflammation Antibodies	>2 publications with LAIR1 and Inflammation
Disease Models, Animal Antibodies	>1 publications with LAIR1 and Disease Models, Animal
Liver Diseases Antibodies	>1 publications with LAIR1 and Liver Diseases
Cell Transformation, Neoplastic Antibodies	>1 publications with LAIR1 and Cell Transformation, Neoplastic
Necrosis Antibodies	>1 publications with LAIR1 and Necrosis

Organs/Tissues associated with LAIR1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>11 publications with LAIR1 and Blood
Bone Antibodies	>1 publications with LAIR1 and Bone
Lymph Node Antibodies	>1 publications with LAIR1 and Lymph Node
Bone Marrow Antibodies	>1 publications with LAIR1 and Bone Marrow
Intestine Antibodies	>1 publications with LAIR1 and Intestine
Connective Tissue Antibodies	>1 publications with LAIR1 and Connective Tissue
Placenta Antibodies	>1 publications with LAIR1 and Placenta
Lung Antibodies	>1 publications with LAIR1 and Lung
Uterus Antibodies	>1 publications with LAIR1 and Uterus