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CKMB Native Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS537589

MBS537589 is a native protein targeting CKMB. Also known as CKMB protein. More details

$1270 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CKMB, Native Protein
Full Product Name
CKMB protein
Product Gene Name
Product Synonym Names
Creatine Kinase-MB Isoenzyme Protein; CK-MB protein
Form/Format
0.2 um filtered, liquid in 10 mM Tris-succinate, 2mM DTT, 2mM EDTA, 175mM NaCl, 50% glycerol, pH 7.0. Contains no preservative
Purity/Purification
> 99% (based on Helena QuickGel CK)
Concentration
Specific CKMB protein: 1.59 mg/ml
1590 U/ml (by Dimension Clinical Chemistry System) (1,000 U = 1 mg CKMB) (lot specific)
Preparation and Storage
Store at 4°C for short term storage. Aliquot and store at -20°C for long term storage. Avoid repeated freeze/thaw cycles.
OMIM
123310
3D Structure
ModBase 3D Structure for P06732
Source
Human heart
Analysis
Total protein: 33 mg/ml (by Coomassie)
Specific CKMB protein: 1.59 mg/ml
Specific activity: 48 U/mg protein
Contaminants
Contains <1% of: GOT, LDH, CKMM, and CKBB
Biohazard
Donor material has been tested and found negative for HBsAg, HCV Ab, HIV 1&2 Ab, and RPR by current FDA approved methods, as well as non-reactive for HIV-1/HCV/HBV by NAT. However, handle with caution as potentially hazardous
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.

Product Categories/Family for CKMB native protein

Other Notes

Small volumes of CKMB native protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CKMB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
creatine kinase M-type
NCBI Official Synonym Full Names
creatine kinase, muscle
NCBI Official Symbol
CKM
NCBI Official Synonym Symbols
CKMM; M-CK
UniProt Protein Name
Creatine kinase M-type
UniProt Synonym Protein Names
Creatine kinase M chain; M-CK
UniProt Gene Name
CKM
UniProt Synonym Gene Names
CKMM
UniProt Entry Name
KCRM_HUMAN
NCBI Protein Information
creatine kinase M-type

NCBI Summary for CKMB

The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq, Jul 2008]
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UniProt Comments for CKMB

CKM: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Belongs to the ATP:guanido phosphotransferase family.

Protein type: EC 2.7.3.2; Amino Acid Metabolism - arginine and proline; Kinase, other

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: cytosol

Molecular Function: creatine kinase activity; ATP binding

Biological Process: phosphocreatine biosynthetic process; phosphorylation; creatine metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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