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PAI2 Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS539367

MBS539367 is an active protein targeting PAI2. Also known as PAI2 protein. Host: Human. Purified recombinant Human PAI2 protein More details

$685 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PAI2, Active Protein
Full Product Name
PAI2 protein
Product Gene Name
Product Synonym Names
Plasminogen Activator Inhibitor-2 protein; Urokinase Inhibitor protein; PAI 2; PAI-2 protein; PAI2; PAI 2 protein; PAI-2
Sequence
Region of PAI2 protein correspond ing to amino acids MEDLCVANTL FALNLFKHLA KASPTQNLFL SPWSISSTMA MVYMGSRGST EDQMAKVLQF NEVGANAVT PMTPENFTSC GFMQQIQKGS YPDAILQAQA ADKIHSSFRS LSSAINASTG N YLLESVNK LFGEKSASFR EEYIRLCQKY YSSEPQAVDF LECAEEARKK INSWVKTQTK GK IPNLLPE GSVDGDTRMV LVNAVYFKGK WKTPFEKKLN GLYPFRVNSA QRTPVQMMYL REK LNIGYI EDLKAQILEL PYAGDVSMFL LLPDEIADVS TGLELLESEI TYDKLNKWTS KDKM AEDEV EVYIPQFKLE EHYELRSILR SMGMEDAFNK GRANFSGMSE RNDLFLSEVF HQAMV DVNE EGTEAAAGTG GVMTGRTGHG GPQFVADHPF LFLIMHKITN CILFFGRFSS P.
Host
Human
Form/Format
Lyophilized from 50MM CH3COONa, with 100mM NaCl. Reconstitute in water to a concentration of 0.1-1.0 mg/ml.
Purity/Purification
> 95% pure
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
46,596 Da
OMIM
173390
3D Structure
ModBase 3D Structure for P05120
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Protein Type
Recombinant
Bioactivity
Determined by its inhibitory effect against single chain tPA induced cleavage of a chromogenic substrate in Imidazole Buffer at 370C. Half maximal inhibition against 1.0 ug/ml of single chain tPA was obtained at a concentration of 1.0 ug/ml
Endotoxin Levels
Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Expression System
E Coli
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.

Product Categories/Family for PAI2 active protein

Applications Tested/Suitable for PAI2 active protein
User optimized

Other Notes

Small volumes of PAI2 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PAI2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
plasminogen activator inhibitor 2
NCBI Official Synonym Full Names
serpin peptidase inhibitor, clade B (ovalbumin), member 2
NCBI Official Symbol
SERPINB2
NCBI Official Synonym Symbols
PAI; PAI2; PAI-2; PLANH2; HsT1201
UniProt Protein Name
Plasminogen activator inhibitor 2
UniProt Synonym Protein Names
Monocyte Arg-serpin; Placental plasminogen activator inhibitor; Serpin B2; Urokinase inhibitor
UniProt Gene Name
SERPINB2
UniProt Synonym Gene Names
PAI2; PLANH2; PAI-2
UniProt Entry Name
PAI2_HUMAN
NCBI Protein Information
plasminogen activator inhibitor 2

UniProt Comments for PAI2

SERPINB2: Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell- derived PAI-1. Belongs to the serpin family. Ov-serpin subfamily.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 18q21.3

Cellular Component: extracellular space; cytoplasm; plasma membrane; extracellular region

Molecular Function: serine-type endopeptidase inhibitor activity

Biological Process: fibrinolysis; blood coagulation; negative regulation of apoptosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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