• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

C10 Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS539389

MBS539389 is an active protein targeting C10. Also known as C10 protein (Mouse). Host: Mouse. Purified recombinant Mouse C10 protein More details

$685 / 0.01 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
C10, Active Protein
Full Product Name
C10 protein (Mouse)
Product Gene Name
C10 active protein
Product Synonym Names
C-10; MRP-1 protein; C10; C-10 protein; C 10; CCL6 protein; C 10 protein
Sequence
Region of C10 protein correspond ing to amino acids GLIQEIEKED RRYNPPIIHQ GFQDTSSDCC FSYATQIPCK RFIYYFPTSG GCIKPGIIFI SRRGTQVCAD PSDRRVQRCL STLKQGPRSG NKVIA.
Host
Mouse
Form/Format
Supplied as a lyophilized powder.
Purity/Purification
> 98% pure
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
10.7 kDa
3D Structure
ModBase 3D Structure for P27784
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Protein Type
Recombinant
Bioactivity
Determined by its ability to chemoattract Balb/c mouse spleen MNCs using a concentration range of 10.0-100.0 ng/ml.
Endotoxin Levels
Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Expression System
E Coli

Product Categories/Family for C10 active protein

Cytokines & Growth Factors
Applications Tested/Suitable for C10 active protein
User optimized

Other Notes

Small volumes of C10 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for C10. It may not necessarily be applicable to this product.

NCBI GI #
6677883
NCBI GeneID
20305
NCBI Accession #
NP_033165.1
UniProt Primary Accession #
P27784
UniProt Secondary Accession #
Q3U3W3; Q5QNW1; Q99M24; Q9D830
UniProt Related Accession #
P27784
GenBank Nucleotide #
NM_009139.3
NCBI Official Full Name
C-C motif chemokine 6
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 6
NCBI Official Symbol
Ccl6
NCBI Official Synonym Symbols
c10; MRP-1; Scya6
UniProt Protein Name
C-C motif chemokine 6
UniProt Synonym Protein Names
Protein C10; Small-inducible cytokine A6
Protein Family
Para-Rep
UniProt Gene Name
Ccl6
UniProt Synonym Gene Names
C10; Scya6
UniProt Entry Name
CCL6_MOUSE
NCBI Protein Information
C-C motif chemokine 6

UniProt Comments for C10

CCL6: Shows chemotactic activity for monocytes, resting T- lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23. Belongs to the intercrine beta (chemokine CC) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis

Cellular Component: extracellular space; extracellular region

Molecular Function: chemokine activity; cytokine activity

Biological Process: immune response; chemotaxis
Show more

Research Articles on C10

1. Mice lacking RXRalpha in myeloid cells exhibit reduced levels of CCL6 and CCL9, impaired recruitment of leukocytes to sites of inflammation, and lower susceptibility to sepsis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with C10 active protein

 Reference Product  PubMed Publications
 Ccl9 active protein  >13 publications with C10 and Ccl9
 Ccl5 active protein  >11 publications with C10 and Ccl5
 Ccr1 active protein  >10 publications with C10 and Ccr1
 Cxcl13 active protein  >5 publications with C10 and Cxcl13
 Ccr5 active protein  >3 publications with C10 and Ccr5
 Cxcl16 active protein  >2 publications with C10 and Cxcl16
 Ccr2 active protein  >2 publications with C10 and Ccr2
 Ccl28 active protein  >1 publications with C10 and Ccl28

Pathways associated with C10 active protein

 Products by Pathway  Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway antibodies  Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram

Diseases associated with C10 active protein

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >28 publications with C10 and Inflammation
 Disease Models, Animal Antibodies  >16 publications with C10 and Disease Models, Animal
 Lung Diseases Antibodies  >11 publications with C10 and Lung Diseases
 Fibrosis Antibodies  >9 publications with C10 and Fibrosis
 Asthma Antibodies  >8 publications with C10 and Asthma
 Respiratory Hypersensitivity Antibodies  >8 publications with C10 and Respiratory Hypersensitivity
 Necrosis Antibodies  >6 publications with C10 and Necrosis
 Liver Diseases Antibodies  >4 publications with C10 and Liver Diseases
 Lung Neoplasms Antibodies  >2 publications with C10 and Lung Neoplasms
 Breast Neoplasms Antibodies  >2 publications with C10 and Breast Neoplasms

Organs/Tissues associated with C10 active protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >39 publications with C10 and Blood
 Lung Antibodies  >19 publications with C10 and Lung
 Liver Antibodies  >7 publications with C10 and Liver
 Intestine Antibodies  >7 publications with C10 and Intestine
 Bone Antibodies  >5 publications with C10 and Bone
 Lymph Node Antibodies  >4 publications with C10 and Lymph Node
 Bone Marrow Antibodies  >4 publications with C10 and Bone Marrow
 Spleen Antibodies  >4 publications with C10 and Spleen
 Muscle Antibodies  >4 publications with C10 and Muscle
 Kidney Antibodies  >3 publications with C10 and Kidney
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000