MIP3 alpha Active Protein

Name: MIP3 alpha Active Protein; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS539403
Price: 695 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS539403

MBS539403 is an active protein targeting MIP3 alpha. Also known as MIP3 alpha protein (Mouse). Host: Mouse. Purified recombinant Mouse MIP3 alpha protein More details

$695 / 0.02 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MIP3 alpha, Active Protein

Full Product Name

MIP3 alpha protein (Mouse)

Product Gene Name

MIP3 alpha active protein

Product Synonym Names

MIP3 alpha; MIP 3 alpha; MIP-3 alpha; Exodus-1 protein; Macrophage Inflammatory Protein-3 alpha protein; MIP-3 alpha protein; MIP 3 alpha protein; CCL20 protein; LARC protein

Sequence

Region of MIP3 alpha protein correspond ing to amino acids ASNYDCCLSY IQTPLPSRAI VGFTRQMADE ACDINAIIFH TKKRKSVCAD PKQNWVKRAV NLLSLRVKKM .

Host

Mouse

Form/Format

Supplied as a lyophilized powder.

Purity/Purification

> 98% pure

Preparation and Storage

Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Molecular Weight

7.9 kDa

3D Structure

ModBase 3D Structure for Q642U4

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Protein Type

Recombinant

Bioactivity

Determined by its ability to chemoattract Mouse CCR6 transfected HEK/293 cells using a concentration range of 0.1-10.0 ng/ml

Endotoxin Levels

Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

Expression System

E Coli

Product Categories/Family for MIP3 alpha active protein

Cytokines & Growth Factors

Applications Tested/Suitable for MIP3 alpha active protein

User optimized

Other Notes

Small volumes of MIP3 alpha active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MIP3 alpha. It may not necessarily be applicable to this product.

NCBI GI #

3907618

NCBI GeneID

20297

NCBI Accession #

AAC78680.1

UniProt Primary Accession #

Q642U4

UniProt Related Accession #

O89093

NCBI Official Full Name

macrophage inflammatory protein 3 alpha

NCBI Official Synonym Full Names

chemokine (C-C motif) ligand 20

NCBI Official Symbol

Ccl20

NCBI Official Synonym Symbols

CKb4; LARC; ST38; MIP3A; MIP-3A; Scya20; MIP-3[a]; exodus-1

UniProt Protein Name

C-C motif chemokine

UniProt Gene Name

Ccl20

UniProt Entry Name

Q642U4_MOUSE

NCBI Protein Information

C-C motif chemokine 20

UniProt Comments for MIP3 alpha

CCL20: Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli 25922 and S.aureus 29213. Belongs to the intercrine beta (chemokine CC) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Chemokine; Secreted, signal peptide; Motility/polarity/chemotaxis

Cellular Component: extracellular space; extracellular region

Molecular Function: protein binding; chemokine activity; cytokine activity

Biological Process: immune response; positive regulation of interleukin-1 alpha biosynthetic process; chemotaxis; inflammatory response; positive regulation of nitric-oxide synthase biosynthetic process

Research Articles on MIP3 alpha

1. Acquired mtDNA mutations may promote tumorigenic phenotypes through up-regulation of chemokine CCL20.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MIP3 alpha active protein

Reference Product	PubMed Publications
Ccr6 active protein	>394 publications with MIP3 alpha and Ccr6
Cxcl10 active protein	>110 publications with MIP3 alpha and Cxcl10
Ccl5 active protein	>98 publications with MIP3 alpha and Ccl5
Cxcl2 active protein	>81 publications with MIP3 alpha and Cxcl2
Cxcl9 active protein	>57 publications with MIP3 alpha and Cxcl9
Cxcl5 active protein	>43 publications with MIP3 alpha and Cxcl5
Ccr5 active protein	>40 publications with MIP3 alpha and Ccr5
Ccl28 active protein	>11 publications with MIP3 alpha and Ccl28
Ccl9 active protein	>5 publications with MIP3 alpha and Ccl9

Pathways associated with MIP3 alpha active protein

Products by Pathway	Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
EBV LMP1 Signaling Pathway antibodies	EBV LMP1 Signaling Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram

Diseases associated with MIP3 alpha active protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>403 publications with MIP3 alpha and Inflammation
Necrosis Antibodies	>216 publications with MIP3 alpha and Necrosis
Skin Diseases Antibodies	>110 publications with MIP3 alpha and Skin Diseases
Carcinoma Antibodies	>89 publications with MIP3 alpha and Carcinoma
Lung Diseases Antibodies	>85 publications with MIP3 alpha and Lung Diseases
Hypersensitivity Antibodies	>60 publications with MIP3 alpha and Hypersensitivity
Asthma Antibodies	>46 publications with MIP3 alpha and Asthma
Liver Diseases Antibodies	>46 publications with MIP3 alpha and Liver Diseases
Neoplasms, Experimental Antibodies	>35 publications with MIP3 alpha and Neoplasms, Experimental
Fibrosis Antibodies	>26 publications with MIP3 alpha and Fibrosis

Organs/Tissues associated with MIP3 alpha active protein

Organ/Tissue Name	Pubmed Publications
Thymus Antibodies	>13 publications with MIP3 alpha and Thymus
Mammary Gland Antibodies	>6 publications with MIP3 alpha and Mammary Gland
Testis Antibodies	>1 publications with MIP3 alpha and Testis