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Eotaxin 2 (CCL24) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS539601

MBS539601 is an active protein targeting Ccl24. Also known as Eotaxin 2 protein. Host: Human. Purified recombinant Human Eotaxin 2 protein More details

$695 / 0.02 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Eotaxin 2 (Ccl24), Active Protein
Full Product Name
Eotaxin 2 protein
Product Gene Name
Ccl24 active protein
Product Synonym Names
Eotaxin-2 protein; MPIF-2 protein; CkB-6 protein; CCL24 protein
Sequence
Region of Eotaxin 2 protein correspond ing to amino acids VVIPSPCCMF FVSKRIPENR VVSYQLSSRS TCLKGGVIFT TKKGQQFCGD PKQEWVQRYM KNLDAKQKKA SPRARAVA.
Host
Human
Form/Format
Supplied as a lyophilized powder.
Purity/Purification
> 98% pure
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
8.8 kDa
3D Structure
ModBase 3D Structure for Q3U0A4
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Protein Type
Recombinant
Bioactivity
Determined by its ability to chemoattract using human peripheral blood eosinophils using a concentration of 50.0-100.0 ng/ml.
Endotoxin Levels
Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Expression System
E Coli

Product Categories/Family for Ccl24 active protein

Cytokines & Growth Factors
Applications Tested/Suitable for Ccl24 active protein
User optimized

Other Notes

Small volumes of Ccl24 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Ccl24. It may not necessarily be applicable to this product.

NCBI GI #
11181622
NCBI GeneID
56221
NCBI Accession #
AAG32664.1
UniProt Primary Accession #
Q3U0A4
UniProt Related Accession #
Q9JKC0
NCBI Official Full Name
eotaxin-2
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 24
NCBI Official Symbol
Ccl24
NCBI Official Synonym Symbols
CKb-6; MPIF-2; Scya24
UniProt Protein Name
C-C motif chemokine
Protein Family
C-C motif chemokine
UniProt Gene Name
Ccl24
UniProt Entry Name
Q3U0A4_MOUSE
NCBI Protein Information
C-C motif chemokine 24

UniProt Comments for Ccl24

CCL24: Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis

Cellular Component: extracellular space; extracellular region

Molecular Function: chemokine activity; cytokine activity

Biological Process: regulation of cell shape; positive regulation of angiogenesis; positive regulation of actin filament polymerization; eosinophil chemotaxis; cytoskeleton organization and biogenesis; immune response; positive regulation of endothelial cell proliferation; chemotaxis; inflammatory response; positive regulation of cell migration; positive regulation of inflammatory response
Show more

Research Articles on Ccl24

1. Autologous transfer of peritoneal macrophages in to the airways of asthmatic mice reduces eotaxin production.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Ccl24 active protein

 Reference Product  PubMed Publications
 Ccr3 active protein  >99 publications with Ccl24 and Ccr3
 Ccr5 active protein  >16 publications with Ccl24 and Ccr5
 Ccr4 active protein  >12 publications with Ccl24 and Ccr4
 Ccr2 active protein  >11 publications with Ccl24 and Ccr2
 Ccr1 active protein  >9 publications with Ccl24 and Ccr1
 Cxcr3 active protein  >7 publications with Ccl24 and Cxcr3
 Cxcr2 active protein  >2 publications with Ccl24 and Cxcr2
 Cxcr5 active protein  >1 publications with Ccl24 and Cxcr5
 Ccr9 active protein  >1 publications with Ccl24 and Ccr9

Pathways associated with Ccl24 active protein

 Products by Pathway  Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram

Diseases associated with Ccl24 active protein

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >123 publications with Ccl24 and Inflammation
 Immune System Diseases Antibodies  >102 publications with Ccl24 and Immune System Diseases
 Hypersensitivity Antibodies  >95 publications with Ccl24 and Hypersensitivity
 Asthma Antibodies  >92 publications with Ccl24 and Asthma
 Respiratory Tract Diseases Antibodies  >91 publications with Ccl24 and Respiratory Tract Diseases
 Lung Diseases Antibodies  >83 publications with Ccl24 and Lung Diseases
 Necrosis Antibodies  >28 publications with Ccl24 and Necrosis
 Skin Diseases Antibodies  >24 publications with Ccl24 and Skin Diseases
 Dermatitis Antibodies  >18 publications with Ccl24 and Dermatitis
 Fibrosis Antibodies  >15 publications with Ccl24 and Fibrosis

Organs/Tissues associated with Ccl24 active protein

 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >9 publications with Ccl24 and Intestine
 Spleen Antibodies  >8 publications with Ccl24 and Spleen
 Thymus Antibodies  >5 publications with Ccl24 and Thymus
 Embryonic Tissue Antibodies  >2 publications with Ccl24 and Embryonic Tissue
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