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TLR12 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5400084

BIOTIN-Conjugated Toll-like receptor 12 AntibodyParticipates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). More details

$610 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TLR12, Polyclonal Antibody
Full Product Name
TLR12 Antibody BIOTIN-Conjugated
Product Gene Name
Product Synonym Names
Toll-like receptor 12
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Chimpanzee, Human, Monkey
Form/Format
BIOTIN-Conjugated
Concentration
0.55-0.69 ug/ul in antibody stabilization buffer (lot specific)
Preparation and Storage
-20 degree C for long term storage
Matching Pairs
Antibody: TLR12 (MBS5400084)
Positive Control: TLR12 (MBS543320)
Antibody/Peptide Pairs
TLR12 peptide (MBS544576) is used for blocking the activity of TLR12 antibody (MBS5400084)
Molecular Weight
99,945 Da
3D Structure
ModBase 3D Structure for Q6QNU9
Immunogen
Synthetic peptide taken within amino acid region 440-470 from mouse TLR12 protein.
Expression
Macrophages, liver, kidney and bladder epithelial cells.
Molecular Function
Receptor
Structure
Binds MYD88 via their respective TIR domains.
Subcellular Location
Membrane; Single-pass type I membrane protein
Applications Tested/Suitable for anti-TLR12 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-TLR12 antibody
Dot Blot: 1:20,000
ELISA: 1:20,000
Western Blot: 1:500

Other Notes

Small volumes of anti-TLR12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TLR12 purchase

MBS5400084 is an antibody targeting TLR12. Also known as TLR12 Antibody BIOTIN-Conjugated. Reactive in Chimpanzee, Human, Monkey. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TLR12. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
toll-like receptor 12
NCBI Official Synonym Full Names
toll-like receptor 12
NCBI Official Symbol
Tlr12
NCBI Official Synonym Symbols
Tlr11; Gm1365
UniProt Protein Name
Toll-like receptor 12
Protein Family
UniProt Gene Name
Tlr12
UniProt Synonym Gene Names
Gm1365
UniProt Entry Name
TLR12_MOUSE
NCBI Protein Information
toll-like receptor 12

UniProt Comments for TLR12

TLR12: Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Plays a role in preventing infection of internal organs of the urogenital system. Belongs to the Toll-like receptor family.

Protein type: Receptor, misc.; Membrane protein, integral

Cellular Component: integral to membrane; membrane

Biological Process: defense response to protozoan; immune response; immune system process; inflammatory response; innate immune response; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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