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CX3CL1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5400375

MBS5400375 is an antibody targeting CX3CL1. Also known as CX3CL1 Antibody. Reactive in Human, Monkey, Mouse, Rat. Host: Rabbit. Affinity Purified Fractalkine Antibody More details

$480 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CX3CL1, Polyclonal Antibody
Full Product Name
CX3CL1 Antibody
Product Gene Name
Product Synonym Names
Affinity Purified Fractalkine Antibody; A 152E5.2 antibody; AB030188 antibody; ABCD3 antibody; AI848747 antibody; C-X3-C motif chemokine 1 antibody; C3Xkine antibody; Chemokine C X3 C motif ligand 1 antibody; CX3C membrane anchored chemokine antibody; Cx3cl1 antibody; CXC3 antibody; CXC3C antibody; D8Bwg0439e antibody; FKN antibody; Fractalkine antibody; Neurotactin antibody; NTN antibody; NTT antibody; Processed fractalkine antibody; SCYD 1 antibody; Small inducible cytokine D1 antibody; X3CL1_HUMAN antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Monkey, Mouse, Rat
Purity/Purification
Affinity Purified
Concentration
Approximately 0.75 mg/ml IgG in antibody stabilization buffer (lot specific). Note: The antibody concentration is approximate and lot specific. The volume of the antibody in the vial is ~200 ul which ensures each vial/lot contains at least 100 ug antibody (lot specific)
Preparation and Storage
Store at -20 degree C for long term storage.
3D Structure
ModBase 3D Structure for O35188
Immunogen
Synthetic peptide taken within amino acid reigon 350-395 on mouse Fractalkine protein.
Conjugation
Unconjugated
Molecular Function
CCR chemokine receptor binding; chemokine activity; CX3C chemokine receptor binding; integrin binding
Subcellular Location
Cell Membrane; Single-pass type I membrane protein; Processed fractalkine: Secreted
Applications Tested/Suitable for anti-CX3CL1 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-CX3CL1 antibody
ELISA: 1:10,000
IHC: 1:50-1:250
ICC/IF: 1:150-1:250
IP: 1:200
WB: 1:500-1:1,000

Western Blot (WB) of anti-CX3CL1 antibody

Rabbit Anti-CX3CL1 Polyclonal Antibody – Cat# MBS5400375

Immunohistochemistry (IHC) of anti-CX3CL1 antibody

Rabbit Anti-CX3CL1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS5400375

Immunohistochemistry (IHC) of anti-CX3CL1 antibody

Rabbit Anti-CX3CL1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS5400375

Immunohistochemistry (IHC) of anti-CX3CL1 antibody

Rabbit Anti-CX3CL1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS5400375

Immunohistochemistry (IHC) of anti-CX3CL1 antibody

Rabbit Anti-CX3CL1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS5400375

Other Notes

Small volumes of anti-CX3CL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CX3CL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
fractalkine
NCBI Official Synonym Full Names
chemokine (C-X3-C motif) ligand 1
NCBI Official Symbol
Cx3cl1
NCBI Official Synonym Symbols
CX3C; Cxc3; Scyd1; ABCD-3; AB030188; AI848747; D8Bwg0439e
UniProt Protein Name
Fractalkine
UniProt Synonym Protein Names
C-X3-C motif chemokine 1; CX3C membrane-anchored chemokine; Neurotactin; Small-inducible cytokine D1
Protein Family
UniProt Gene Name
Cx3cl1
UniProt Synonym Gene Names
Cx3c; Fkn; Scyd1
NCBI Protein Information
fractalkine

UniProt Comments for CX3CL1

Acts as a ligand for both CX3CR1 and integrins. Binds to CX3CR1 and to integrins ITGAV:ITGB3 and ITGA4:ITGB1. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins. In the absence of CX3CR1, binds to a second site (site 2) in integrins which is distinct from site 1 and enhances the binding of other integrin ligands to site 1 (). The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium (PubMed:9177350, PubMed:10382755).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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