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PDE7B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS540084

Affinity Purified cAMP-specific 3', 5'-cyclic phosphodiesterase 7B AntibodyHydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in the control of cAMP-mediated neural activity and cAMP… More details

$540 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
PDE7B, Polyclonal Antibody
Full Product Name
Pan PDE7B Antibody Affinity Purified
Product Gene Name
Product Synonym Names
bA472E5.1; cAMP specific 3 5 cyclic phosphodiesterase 7B; High affinity cAMP specific 3 5 cyclic phosphodiesterase; MGC88256; PDE 7B; Phosphodiesterase7B; RNPDE7B; Rolipram insensitive phosphodiesterase type 7 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Affinity Purified
Concentration
0.5 ug/ul in antibody stabilization buffer (lot specific)
Preparation and Storage
-20 degree C for long term storage
Matching Pairs
Antibody: PDE7B (MBS540084)
Positive Control: PDE7B (MBS543100)
Antibody/Peptide Pairs
PDE7B peptide (MBS544229) is used for blocking the activity of PDE7B antibody (MBS540084)
Molecular Weight
51,835 Da
OMIM
604645
3D Structure
ModBase 3D Structure for Q9NP56
Immunogen
Synthetic cyclic peptide common to all PDE7B variants.
Expression
Highly expressed in brain. Also expressed in heart, liver, skeletal muscle and pancreas.
Molecular Function
Hydrolase, 3', 5' -cyclic-AMP phosphodiesterase activity
Subcellular Location
Cytosol
Applications Tested/Suitable for anti-PDE7B antibody
Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), IMM, Western Blot (WB)
Application Notes for anti-PDE7B antibody
Confocal Microscopy||1:200
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunocytochemistry: 1:200
Immunofluorescence: 1:200
Immunohistochemistry: 1:200
Immunoprecipitation: 1:250
Western Blot: 1:500-1:1,000

Western Blot (WB) of anti-PDE7B antibody

Rabbit Anti-PDE7B Polyclonal Antibody – Cat# MBS540084

Immunohistochemistry (IHC) of anti-PDE7B antibody

Rabbit Anti-PDE7B Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS540084

Other Notes

Small volumes of anti-PDE7B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PDE7B purchase

MBS540084 is an antibody targeting PDE7B. Also known as Pan PDE7B Antibody Affinity Purified. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PDE7B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
cAMP-specific 3',5'-cyclic phosphodiesterase 7B
NCBI Official Synonym Full Names
phosphodiesterase 7B
NCBI Official Symbol
PDE7B
NCBI Official Synonym Symbols
bA472E5.1
UniProt Protein Name
cAMP-specific 3',5'-cyclic phosphodiesterase 7B
UniProt Gene Name
PDE7B
UniProt Entry Name
PDE7B_HUMAN
NCBI Protein Information
cAMP-specific 3',5'-cyclic phosphodiesterase 7B

NCBI Summary for PDE7B

The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.[provided by RefSeq, Apr 2009]
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UniProt Comments for PDE7B

PDE7B: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain. Belongs to the cyclic nucleotide phosphodiesterase family. PDE7 subfamily.

Protein type: Phosphodiesterase; EC 3.1.4.53; Nucleotide Metabolism - purine

Chromosomal Location of Human Ortholog: 6q23-q24

Cellular Component: cytosol

Molecular Function: 3',5'-cyclic-AMP phosphodiesterase activity; metal ion binding

Biological Process: cAMP catabolic process; signal transduction; synaptic transmission
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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