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PGCG Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS540095

Affinity Purified Guanylyl Cyclase G AntibodyBinds to a yet not identified ligand.Possible role in processes such as water and electrolyte balance, and muscle contraction. More details

$540 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PGCG, Polyclonal Antibody
Full Product Name
PGCG Antibody
Product Gene Name
Product Synonym Names
CYGF; GC F; guanylate cyclase 2D-like, membrane (retina-specific); Guanylate cyclase 2F; GUC2DL; GUC2F; Gucy2f; RETGC-2; retinal; Rod outer segment membrane guanylate cyclase 2; ROS-GC2 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Affinity Purified
Concentration
0.75-1.20 ug/ul in antibody stabilization buffer (lot specific)
Preparation and Storage
-20 degree C for long term storage
Matching Pairs
Antibody: PGCG (MBS540095)
Positive Control: PGCG (MBS543120)
Antibody/Peptide Pairs
PGCG peptide (MBS544259) is used for blocking the activity of PGCG antibody (MBS540095)
Molecular Weight
48,319 Da
3D Structure
ModBase 3D Structure for P55205
Immunogen
Synthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase G protein.
Expression
Expressed in lung, kidney and skeletal muscle. Low levels in intestine.
Molecular Function
Lyase, Receptor
Structure
Homodimer or heterodimer with NPR1.
Subcellular Location
Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Cytoplasm
Applications Tested/Suitable for anti-PGCG antibody
Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-PGCG antibody
Confocal Microscopy||1:200
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunocytochemistry: 1:200
Immunofluorescence: 1:200
Immunohistochemistry: 1:200
Western Blot: 1:500

Immunofluorescence (IF) of anti-PGCG antibody

Rabbit Anti-PGCG Polyclonal Antibody – Cat# MBS540095

Immunofluorescence (IF) of anti-PGCG antibody

Rabbit Anti-PGCG Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS540095

Immunofluorescence (IF) of anti-PGCG antibody

Rabbit Anti-PGCG Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS540095

Other Notes

Small volumes of anti-PGCG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PGCG purchase

MBS540095 is an antibody targeting PGCG. Also known as PGCG Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PGCG. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
NCBI Official Full Name
Rattus norvegicus guanylyl cyclase-G (GC-G) mRNA, complete cds
UniProt Protein Name
Guanylate cyclase 2G
UniProt Synonym Protein Names
Guanylyl cyclase receptor G; GC-G; Kinase-like domain-containing soluble guanylyl cyclase; ksGC
UniProt Gene Name
Gucy2g
UniProt Synonym Gene Names
Ksgc; GC-G; ksGC
UniProt Entry Name
GUC2G_RAT

UniProt Comments for PGCG

Gucy2g: a receptor with two intracellular enzymatic activities: a protein kinase of the RGC group and a guanylyl cyclase of the adenylyl cyclase class-4/guanylyl cyclase family. Probably plays a specific functional role in the testis by binding to yet not identified ligand.

Protein type: Lyase; Guanylyl cyclase; Membrane protein, integral; EC 4.6.1.2

Cellular Component: external side of plasma membrane; guanylate cyclase complex, soluble; integral to membrane; intracellular; plasma membrane

Molecular Function: adenylate cyclase activity; ATP binding; GTP binding; guanylate cyclase activity; protein kinase activity

Biological Process: cGMP biosynthetic process; protein amino acid phosphorylation; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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