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CCR7 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS540572

MBS540572 is an antibody targeting CCR7. Also known as CCR7 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. Affinity Purified C-C chemokine receptor type 7 precursor Antibody More details

$480 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CCR7, Polyclonal Antibody
Full Product Name
CCR7 Antibody
Product Gene Name
anti-CCR7 antibody
Product Synonym Names
BLR 2; C C chemokine receptor type 7; C C CKR 7; CCR 7; CD 197; CDW197; CMKBR7; EBI 1; EBV Induced G Protein Coupled Receptor 1; Epstein Barr virus induced G protein coupled receptor; EVI 1; Lymphocyte Specific G Protein Coupled Peptide Receptor; MGC108519; MIP3 Beta Receptor antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Affinity Purified
Concentration
0.65-1.25 ug/ul in antibody stabilization buffer (lot specific)
Preparation and Storage
-20 degree C for long term storage
Matching Pairs
Antibody: CCR7 (MBS540572)
Positive Control: CCR7 (MBS542611)
Antibody/Peptide Pairs
CCR7 peptide (MBS542656) is used for blocking the activity of CCR7 antibody (MBS540572)
Molecular Weight
42,822 Da
3D Structure
ModBase 3D Structure for Q6U2D6
Immunogen
Synthetic peptide corresponding to unique amino acid sequence on CCR7 protein.
Molecular Function
G-protein coupled receptor
Structure
Belongs to G-protein coupled receptor 1 family; Transmembrane helix
Subcellular Location
Membrane

Product Categories/Family for anti-CCR7 antibody

Primary Antibodies; Immunology; Innate Immunity; Chemokines; CCR7 Antibody
Applications Tested/Suitable for anti-CCR7 antibody
Confocal Microscopy (CM), Dot Blot (DB), ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-CCR7 antibody
Confocal Microscopy||1:250
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunocytochemistry: 1:250
Immunofluorescence: 1:250
Immunohistochemistry: 1:250
Western Blot: 1:500

Western Blot (WB) of anti-CCR7 antibody

Rabbit Anti-CCR7 Polyclonal Antibody – Cat# MBS540572

Immunohistochemistry (IHC) of anti-CCR7 antibody

Rabbit Anti-CCR7 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS540572

Immunohistochemistry (IHC) of anti-CCR7 antibody

Rabbit Anti-CCR7 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS540572

Other Notes

Small volumes of anti-CCR7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CCR7. It may not necessarily be applicable to this product.

NCBI GI #
41054914
NCBI GeneID
287673
NCBI Accession #
NP_955783
UniProt Primary Accession #
Q6U2D6
GenBank Nucleotide #
NM_199489.4
NCBI Official Full Name
C-C chemokine receptor type 7
NCBI Official Synonym Full Names
C-C motif chemokine receptor 7
NCBI Official Symbol
Ccr7
UniProt Protein Name
Chemokine (C-C motif) receptor 7
UniProt Synonym Protein Names
Chemokine (C-C motif) receptor 7
Protein Family
C-C chemokine receptor
UniProt Gene Name
Ccr7
UniProt Entry Name
Q6U2D6_RAT
NCBI Protein Information
C-C chemokine receptor type 7

NCBI Summary for CCR7

mouse homolog is a chemokine receptor; involved in the immune response to viruses [RGD, Feb 2006]

UniProt Comments for CCR7

CCR7: Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Motility/polarity/chemotaxis; Membrane protein, integral

Cellular Component: cell surface; external side of plasma membrane; integral to membrane; intracellular; plasma membrane

Molecular Function: C-C chemokine receptor activity

Biological Process: chemotaxis; G-protein coupled receptor protein signaling pathway; homeostasis of number of cells; immune response; inflammatory response; myeloid dendritic cell chemotaxis; negative thymic T cell selection; positive regulation of dendritic cell antigen processing and presentation; positive regulation of humoral immune response; positive regulation of hypersensitivity; positive regulation of interleukin-12 production; positive regulation of T cell receptor signaling pathway; regulation of interferon-gamma production; regulation of interleukin-1 beta secretion; response to lipopolysaccharide
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Research Articles on CCR7

1. CCL19/CCR7 contributes to the migration of bone marrow mesenchymal stem cells by upregulating MMP9 potentially via the PI3K/Akt pathway.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CCR7 antibody

 Reference Product  PubMed Publications
 Ccl21 antibody  >549 publications with CCR7 and Ccl21
 Ccl19 antibody  >511 publications with CCR7 and Ccl19
 Cd40 antibody  >238 publications with CCR7 and Cd40
 Cxcl12 antibody  >173 publications with CCR7 and Cxcl12
 Cxcl13 antibody  >59 publications with CCR7 and Cxcl13
 Ccl4 antibody  >55 publications with CCR7 and Ccl4
 Ccl25 antibody  >23 publications with CCR7 and Ccl25
 Ccl27 antibody  >19 publications with CCR7 and Ccl27
 S1pr1 antibody  >11 publications with CCR7 and S1pr1

Pathways associated with anti-CCR7 antibody

 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram

Diseases associated with anti-CCR7 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >436 publications with CCR7 and Inflammation
 Necrosis Antibodies  >253 publications with CCR7 and Necrosis
 Disease Models, Animal Antibodies  >167 publications with CCR7 and Disease Models, Animal
 Lung Diseases Antibodies  >141 publications with CCR7 and Lung Diseases
 Hypersensitivity Antibodies  >115 publications with CCR7 and Hypersensitivity
 Liver Diseases Antibodies  >79 publications with CCR7 and Liver Diseases
 Neoplasms, Experimental Antibodies  >65 publications with CCR7 and Neoplasms, Experimental
 Breast Neoplasms Antibodies  >54 publications with CCR7 and Breast Neoplasms
 Fibrosis Antibodies  >48 publications with CCR7 and Fibrosis
 Atherosclerosis Antibodies  >47 publications with CCR7 and Atherosclerosis

Organs/Tissues associated with anti-CCR7 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >209 publications with CCR7 and Lung
 Thymus Antibodies  >114 publications with CCR7 and Thymus
 Prostate Antibodies  >21 publications with CCR7 and Prostate
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