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Pannexin 1 (PANX1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS540817

Affinity Purified ECEL1 AntibodyMay play a role in the degradation of peptide hormones. It also may contribute to the inactivation of neuronal peptides. More details

$480 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Pannexin 1 (PANX1), Polyclonal Antibody
Full Product Name
Pannexin 1 Antibody Affinity Purified
Product Gene Name
anti-PANX1 antibody
Product Synonym Names
innexin; MRS1; Pannexin 1; Panx1; UNQ2529 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Affinity Purified
Concentration
0.55 ug/ul in antibody stabilization buffer (lot specific)
Preparation and Storage
-20 degree C for long term storage
Matching Pairs
Antibody: Pannexin 1 (MBS540817)
Positive Control: Pannexin 1 (MBS543036)
Antibody/Peptide Pairs
Pannexin 1 peptide (MBS544114) is used for blocking the activity of Pannexin 1 antibody (MBS540817)
Molecular Weight
47,635 Da
OMIM
608420
3D Structure
ModBase 3D Structure for Q96RD7
Immunogen
Synthetic peptide taken within amino acid region from human Pannexin 1 protein
Subcellular Location
Membrane; Single-pass type II membrane protein

Product Categories/Family for anti-PANX1 antibody

Primary Antibodies; Signal Transduction; Cytoskeleton/ECM; Pannexin 1 Antibody
Applications Tested/Suitable for anti-PANX1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-PANX1 antibody
Dot Blot: 1:10,000
ELISA: 1:10,000
Western Blot: 1:500

Western Blot (WB) of anti-PANX1 antibody

Rabbit Anti-PANX1 Polyclonal Antibody – Cat# MBS540817

Other Notes

Small volumes of anti-PANX1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PANX1 purchase

MBS540817 is an antibody targeting PANX1. Also known as Pannexin 1 Antibody Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PANX1. It may not necessarily be applicable to this product.

NCBI GI #
37182964
NCBI Accession #
AAQ89282.1
UniProt Primary Accession #
Q96RD7
UniProt Secondary Accession #
O75968; Q543A0; Q6UW26; Q96AM9; Q96L77; Q96RS5
NCBI Official Full Name
ECEL1
UniProt Protein Name
Pannexin-1
Protein Family
Pannexin
UniProt Gene Name
PANX1
UniProt Synonym Gene Names
MRS1
UniProt Entry Name
PANX1_HUMAN

UniProt Comments for PANX1

PANX1: Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis. Belongs to the pannexin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 11q21

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; gap junction; integral to membrane; membrane; plasma membrane; protein complex

Molecular Function: actin filament binding; calcium channel activity; gap junction hemi-channel activity; leak channel activity; protease binding; protein heterodimerization activity; receptor binding

Biological Process: calcium ion transport; cation transport; cell-cell signaling; positive regulation of interleukin-1 alpha secretion; positive regulation of interleukin-1 beta secretion; response to ATP
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PANX1 antibody

 Reference Product  PubMed Publications
 PANX2 antibody  >45 publications with PANX1 and PANX2
 CASP1 antibody  >22 publications with PANX1 and CASP1
 P2RX7 antibody  >17 publications with PANX1 and P2RX7
 NLRP3 antibody  >11 publications with PANX1 and NLRP3
 CASP7 antibody  >4 publications with PANX1 and CASP7
 SUGT1 antibody  >1 publications with PANX1 and SUGT1

Diseases associated with anti-PANX1 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >44 publications with PANX1 and Inflammation
 Disease Models, Animal Antibodies  >18 publications with PANX1 and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >14 publications with PANX1 and Cardiovascular Diseases
 Necrosis Antibodies  >10 publications with PANX1 and Necrosis
 Fibrosis Antibodies  >7 publications with PANX1 and Fibrosis
 Nerve Degeneration Antibodies  >7 publications with PANX1 and Nerve Degeneration
 Lung Diseases Antibodies  >4 publications with PANX1 and Lung Diseases
 Fatty Liver Antibodies  >3 publications with PANX1 and Fatty Liver
 Heart Diseases Antibodies  >3 publications with PANX1 and Heart Diseases
 Learning Disorders Antibodies  >2 publications with PANX1 and Learning Disorders

Organs/Tissues associated with anti-PANX1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >95 publications with PANX1 and Brain
 Muscle Antibodies  >30 publications with PANX1 and Muscle
 Eye Antibodies  >26 publications with PANX1 and Eye
 Vascular Antibodies  >20 publications with PANX1 and Vascular
 Embryonic Tissue Antibodies  >15 publications with PANX1 and Embryonic Tissue
 Skin Antibodies  >10 publications with PANX1 and Skin
 Kidney Antibodies  >8 publications with PANX1 and Kidney
 Mouth Antibodies  >8 publications with PANX1 and Mouth
 Bone Antibodies  >7 publications with PANX1 and Bone
 Lung Antibodies  >7 publications with PANX1 and Lung
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