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TM6SF2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS540831

Transmembrane 6 superfamily member 2 (TM6SF2) is a 377 amino acid multi-pass membrane protein that belongs to the TM6SF family which is intricately involved in chemokine signal transduction pathways. TM6SF2, a gene expressed predominantly in liver and… More details

$480 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TM6SF2, Polyclonal Antibody
Full Product Name
TM6SF2 Antibody
Product Gene Name
anti-TM6SF2 antibody
Product Synonym Names
TM6S2_HUMAN; tm6sf2; Transmembrane 6 superfamily member 2 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Affinity Purified
Concentration
0.68 mg/ml IgG in antibody stabilization buffer (lot specific)
Preparation and Storage
-20 degree C for long term storage
Matching Pairs
Antibody: TM6SF2 (MBS540831)
Positive Control: TM6SF2 (MBS543329)
Antibody/Peptide Pairs
TM6SF2 peptide (MBS544585) is used for blocking the activity of TM6SF2 antibody (MBS540831)
Molecular Weight
39,417 Da
OMIM
606563
3D Structure
ModBase 3D Structure for Q8R1J1
Immunogen
Synthetic peptide taken within amino acid region 220-270 on mouse TM6SF2 protein.
Molecular Function
Integral component of membrane
Structure
Transmembrane helix; Belongs to TM6SF family

Product Categories/Family for anti-TM6SF2 antibody

Primary Antibodies; Cell Biology; TM6SF2 Antibody
Applications Tested/Suitable for anti-TM6SF2 antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-TM6SF2 antibody
ELISA: 1:4,000
Immunoprecipitation: 1:150
Western Blot: 1:500

Note: Dilutions are for reference only. Applications not listed above are not necessarily precluded from working with this antibody. investigators intending to use an application that has not beer. verified can request a complimentary sample.

Western Blot (WB) of anti-TM6SF2 antibody

Rabbit Anti-TM6SF2 Polyclonal Antibody – Cat# MBS540831

Western Blot (WB) of anti-TM6SF2 antibody

Rabbit Anti-TM6SF2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS540831

Western Blot (WB) of anti-TM6SF2 antibody

Rabbit Anti-TM6SF2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS540831

Other Notes

Small volumes of anti-TM6SF2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TM6SF2 purchase

MBS540831 is an antibody targeting TM6SF2. Also known as TM6SF2 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TM6SF2. It may not necessarily be applicable to this product.

NCBI GI #
112181177
NCBI GeneID
53345
NCBI Accession #
NP_001001524
UniProt Primary Accession #
Q8R1J1
UniProt Secondary Accession #
Q0IJ64
UniProt Related Accession #
Q9BZW4
GenBank Nucleotide #
NM_001001524.2
NCBI Official Full Name
transmembrane 6 superfamily member 2
NCBI Official Synonym Full Names
transmembrane 6 superfamily member 2
NCBI Official Symbol
TM6SF2
UniProt Protein Name
Transmembrane 6 superfamily member 2
Protein Family
Transmembrane 6 superfamily
UniProt Gene Name
TM6SF2
UniProt Entry Name
TM6S2_HUMAN
NCBI Protein Information
transmembrane 6 superfamily member 2

UniProt Comments for TM6SF2

TM6SF2: Belongs to the TM6SF family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 19p13.3-p12

Cellular Component: endoplasmic reticulum membrane; ER-Golgi intermediate compartment membrane; integral to membrane

Biological Process: lipid metabolic process; regulation of lipid metabolic process
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Research Articles on TM6SF2

1. The rs58542926 SNP in the TM6SF2 gene is associated with pediatric nonalcoholic fatty liver disease but may confer protection against cardiovascular risk

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-TM6SF2 antibody

 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >47 publications with TM6SF2 and Fatty Liver
 Non-alcoholic Fatty Liver Disease Antibodies  >34 publications with TM6SF2 and Non-alcoholic Fatty Liver Disease
 Liver Diseases Antibodies  >24 publications with TM6SF2 and Liver Diseases
 Fibrosis Antibodies  >19 publications with TM6SF2 and Fibrosis
 Carcinoma, Hepatocellular Antibodies  >9 publications with TM6SF2 and Carcinoma, Hepatocellular
 Liver Cirrhosis, Alcoholic Antibodies  >8 publications with TM6SF2 and Liver Cirrhosis, Alcoholic
 Inflammation Antibodies  >5 publications with TM6SF2 and Inflammation
 Heart Diseases Antibodies  >2 publications with TM6SF2 and Heart Diseases
 Nervous System Diseases Antibodies  >2 publications with TM6SF2 and Nervous System Diseases
 Myocardial Infarction Antibodies  >2 publications with TM6SF2 and Myocardial Infarction

Organs/Tissues associated with anti-TM6SF2 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >51 publications with TM6SF2 and Liver
 Brain Antibodies  >2 publications with TM6SF2 and Brain
 Intestine Antibodies  >2 publications with TM6SF2 and Intestine
 Testis Antibodies  >1 publications with TM6SF2 and Testis
 Spleen Antibodies  >1 publications with TM6SF2 and Spleen
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