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STIM2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS540915

Affinity Purified STIM2 protein AntibodyPlays a role in mediating store-operated Ca2+ entry, a Ca2+ influx following depletion of intracellular Ca2+ stores. Regulates basal cytosolic and endoplasmic reticulum Ca2+ concentrations. More details

$480 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
STIM2, Polyclonal Antibody
Full Product Name
STIM2 Antibody Affinity Purified
Product Gene Name
Product Synonym Names
FLJ39527; KIAA1482; stromal interaction molecule 2 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Affinity Purified
Concentration
0.51-0.58 ug/ul in antibody stabilization buffer (lot specific)
Preparation and Storage
-20 degree C for long term storage
Matching Pairs
Antibody: STIM2 (MBS540915)
Positive Control: STIM2 (MBS543288)
Antibody/Peptide Pairs
STIM2 peptide (MBS544532) is used for blocking the activity of STIM2 antibody (MBS540915)
Molecular Weight
68,026 Da
OMIM
610841
3D Structure
ModBase 3D Structure for Q9P246
Immunogen
Synthetic peptide taken within amino acid region 600-650 on human STIM2 protein.
Expression
Expressed in all tissues and tumor cell lines examined.
Molecular Function
Calcium channel regulator activity, calcium ion binding, store-operated calcium channel activity
Subcellular Location
Endoplasmic Reticulum membrane, Single-pass type I membrane protein. (Note: Dynamically translocates from a uniform Endoplasmic Reticulum distribution to punctual Endoplasmic Reticulum-Plasma membrane junctions in response to decrease in endoplasmic retic
Applications Tested/Suitable for anti-STIM2 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-STIM2 antibody
Dot Blot: 1:10,000
ELISA: 1:10,000
Western Blot: 1:500

Western Blot (WB) of anti-STIM2 antibody

Rabbit Anti-STIM2 Polyclonal Antibody – Cat# MBS540915

Other Notes

Small volumes of anti-STIM2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for STIM2 purchase

MBS540915 is an antibody targeting STIM2. Also known as STIM2 Antibody Affinity Purified. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for STIM2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
STIM2 protein
NCBI Official Synonym Full Names
stromal interaction molecule 2
NCBI Official Symbol
STIM2
UniProt Protein Name
Stromal interaction molecule 2
UniProt Gene Name
STIM2
UniProt Synonym Gene Names
KIAA1482
UniProt Entry Name
STIM2_HUMAN
NCBI Protein Information
stromal interaction molecule 2

NCBI Summary for STIM2

This gene is a member of the stromal interaction molecule (STIM) family and likely arose, along with related family member STIM1, from a common ancestral gene. The encoded protein functions to regulate calcium concentrations in the cytosol and endoplasmic reticulum, and is involved in the activation of plasma membrane Orai Ca(2+) entry channels. This gene initiates translation from a non-AUG (UUG) start site. A signal peptide is cleaved from the resulting protein. Multiple transcript variants result from alternative splicing. [provided by RefSeq, Dec 2009]
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UniProt Comments for STIM2

Plays a role in mediating store-operated Ca2+ entry (SOCE), a Ca2+ influx following depletion of intracellular Ca2+ stores. Functions as a highly sensitive Ca2+ sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca2+-influx. Regulates basal cytosolic and endoplasmic reticulum Ca2+ concentrations. Upon mild variations of the endoplasmic reticulum Ca2+ concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca2+ release-activated Ca2+ (CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca2+ influx.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-STIM2 antibody

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