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CXCR1 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS541332

BIOTIN-Conjugated Chemokine (C-X-C motif) receptor 1 AntibodyReceptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that… More details

$610 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CXCR1, Polyclonal Antibody
Full Product Name
CXCR1 Antibody BIOTIN-Conjugated
Product Gene Name
anti-CXCR1 antibody
Product Synonym Names
C C; C C CKR 1; C-X-C chemokine receptor type 1; CCCKR1; CD 181; CD128; CKR 1; CMKAR1; CXC-R1; High affinity interleukin-8 receptor A; IL 8 receptor type 1; IL 8R A antibody
Clonality
Polyclonal
Host
Goat
Species Reactivity
Mouse
Form/Format
BIOTIN-Conjugated
Concentration
0.50-1.2 ug/ul in antibody stabilization buffer (lot specific)
Preparation and Storage
-20 degree C for long term storage
Antibody/Peptide Pairs
CXCR1 peptide (MBS543387) is used for blocking the activity of CXCR1 antibody (MBS541332)
Molecular Weight
40,032 Da
3D Structure
ModBase 3D Structure for Q810W6
Immunogen
Synthetic peptide corresponding to unique amino acid sequences on mouse CXCR1 protein.
Molecular Function
Chemotaxis
Structure
Belongs to the G-protein coupled receptor 1 family
Subcellular Location
Cell membrane; Multi-pass membrane protein
Applications Tested/Suitable for anti-CXCR1 antibody
ELISA (EIA), IMM, Western Blot (WB)
Application Notes for anti-CXCR1 antibody
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunoprecipitation: 1:250
Western Blot: 1:500

Other Notes

Small volumes of anti-CXCR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CXCR1 purchase

MBS541332 is an antibody targeting CXCR1. Also known as CXCR1 Antibody BIOTIN-Conjugated. Reactive in Mouse. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for CXCR1. It may not necessarily be applicable to this product.

NCBI GI #
81913011
NCBI GeneID
227288
NCBI Accession #
Q810W6.1
UniProt Primary Accession #
Q810W6
UniProt Related Accession #
Q810W6
GenBank Nucleotide #
NM_178241.4
NCBI Official Full Name
C-X-C chemokine receptor type 1
NCBI Official Synonym Full Names
chemokine (C-X-C motif) receptor 1
NCBI Official Symbol
Cxcr1
NCBI Official Synonym Symbols
Il8ra
UniProt Protein Name
C-X-C chemokine receptor type 1
UniProt Synonym Protein Names
High affinity interleukin-8 receptor A; IL-8R A; CD_antigen: CD181
Protein Family
C-X-C chemokine receptor
UniProt Gene Name
Cxcr1
UniProt Synonym Gene Names
Il8ra; CXC-R1; CXCR-1; IL-8R A
UniProt Entry Name
CXCR1_MOUSE
NCBI Protein Information
C-X-C chemokine receptor type 1

UniProt Comments for CXCR1

IL8RA: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; GPCR, family 1; Receptor, cytokine; Membrane protein, multi-pass; Membrane protein, integral

Cellular Component: integral to membrane; membrane; plasma membrane

Molecular Function: C-X-C chemokine receptor activity; G-protein coupled receptor activity; interleukin-8 binding; interleukin-8 receptor activity; signal transducer activity

Biological Process: cell surface receptor linked signal transduction; chemotaxis; G-protein coupled receptor protein signaling pathway; receptor internalization; signal transduction
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Research Articles on CXCR1

1. in view of recently-published experimental data obtained in NOD mice, we argue for possible Cxcr1 involvement in type 1 diabetes pathogenesi

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CXCR1 antibody

 Reference Product  PubMed Publications
 Cxcl1 antibody  >123 publications with CXCR1 and Cxcl1
 Ccl5 antibody  >39 publications with CXCR1 and Ccl5
 Cxcr5 antibody  >31 publications with CXCR1 and Cxcr5
 Cxcl2 antibody  >31 publications with CXCR1 and Cxcl2
 Cxcl5 antibody  >27 publications with CXCR1 and Cxcl5
 Ccr8 antibody  >16 publications with CXCR1 and Ccr8
 Ccr10 antibody  >9 publications with CXCR1 and Ccr10
 Ccl20 antibody  >9 publications with CXCR1 and Ccl20
 Cxcr6 antibody  >8 publications with CXCR1 and Cxcr6
 Ccl28 antibody  >1 publications with CXCR1 and Ccl28

Pathways associated with anti-CXCR1 antibody

 Products by Pathway  Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Non-odorant GPCRs Pathway antibodies  Non-odorant GPCRs Pathway Diagram
 Phospholipase D Signaling Pathway antibodies  Phospholipase D Signaling Pathway Diagram
 Phospholipase D Signaling Pathway antibodies  Phospholipase D Signaling Pathway Diagram

Diseases associated with anti-CXCR1 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >266 publications with CXCR1 and Inflammation
 Lung Diseases Antibodies  >89 publications with CXCR1 and Lung Diseases
 Necrosis Antibodies  >79 publications with CXCR1 and Necrosis
 Skin Diseases Antibodies  >51 publications with CXCR1 and Skin Diseases
 Disease Models, Animal Antibodies  >46 publications with CXCR1 and Disease Models, Animal
 Nervous System Diseases Antibodies  >41 publications with CXCR1 and Nervous System Diseases
 Adenocarcinoma Antibodies  >26 publications with CXCR1 and Adenocarcinoma
 Kidney Diseases Antibodies  >23 publications with CXCR1 and Kidney Diseases
 Neoplasm Invasiveness Antibodies  >22 publications with CXCR1 and Neoplasm Invasiveness
 Fibrosis Antibodies  >20 publications with CXCR1 and Fibrosis

Organs/Tissues associated with anti-CXCR1 antibody

 Organ/Tissue Name  Pubmed Publications
 Extraembryonic Tissue Antibodies  >2 publications with CXCR1 and Extraembryonic Tissue
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