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D2 Receptor (DRD2) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS541392

BIOTIN-Conjugated Dopamine Receptor subtype D2 AntibodyDopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. More details

$610 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
D2 Receptor (Drd2), Polyclonal Antibody
Full Product Name
Dopamine D2 Receptor Antibody BIOTIN-Conjugated
Product Gene Name
Product Synonym Names
D(2) dopamine receptor; D2 dopamine receptor; D2DR; D2R; Dopamine D2 receptor; DRD2 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse, Rat
Form/Format
BIOTIN-Conjugated
Concentration
0.55ug/ul in antibody stabilization buffer (lot specific)
Preparation and Storage
-20 degree C for long term storage
Matching Pairs
Antibody/Peptide Pairs
Molecular Weight
20,091 Da
3D Structure
ModBase 3D Structure for Q6LDH7
Immunogen
Synthetic peptide taken within amino acid region 150-200 on rat Dopamine Receptor D2 protein.
Immunoglobulin
IgG
Molecular Function
Dopamine Binding; Potassium Channel Regulator activity; Identical Protein binding
Structure
Forms homo- and heterooligomers with DRD4. The interaction with DRD4 may modulate agonist-induced downstream signaling. Interacts with GPRASP1, PPP1R9B and CLIC6 (By similarity). Interacts with CADPS and CADPS2. Interacts with ARRB2 (By similarity). Interacts with KCNA2 (By similarity). Interacts with GNAI1 (PubMed:17264214). Interacts with GNAI2 isoform sGi2, the interaction allows the creation of an intracellular pool of DRD2 that can be released to cell surface upon agonist stimulation. Interacts with HTR2A.
Subcellular Location
Cell membrane; Multi-pass membrane protein
Applications Tested/Suitable for anti-Drd2 antibody
Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-Drd2 antibody
ELISA: 1:50,000
Immunocytochemistry: 1:200
Immunofluorescence: 1:200
Immunohistochemistry: 1:200
Immunoprecipitation: 1:200
Western Blot: 1:1,000-1:1,5000

Other Notes

Small volumes of anti-Drd2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Drd2 purchase

MBS541392 is an antibody targeting Drd2. Also known as Dopamine D2 Receptor Antibody BIOTIN-Conjugated. Reactive in Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Drd2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
dopamine receptor subtype D2
NCBI Official Synonym Full Names
dopamine receptor D2
NCBI Official Symbol
Drd2
UniProt Protein Name
D(2) dopamine receptor
UniProt Synonym Protein Names
D(2) dopamine receptor
UniProt Gene Name
DRD2
UniProt Entry Name
Q6LDH7_HUMAN
NCBI Protein Information
D(2) dopamine receptor

NCBI Summary for Drd2

mediates G-protein coupled signaling; may be involved in movement disorders, schizophrenia, and drug addiction [RGD, Feb 2006]

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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