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DOC2B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS541433

BIOTIN-Conjugated Double C2-like domain-containing protein beta Antibodycalcium ion-dependent exocytosis of neurotransmitter;positive regulation of insulin secretion More details

$610 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DOC2B, Polyclonal Antibody
Full Product Name
DOC2B Antibody BIOTIN-Conjugated
Product Gene Name
Product Synonym Names
Double C2-like domain-containing protein beta; OTTMUSP00000006522; RP23 78H4.2 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
BIOTIN-Conjugated
Concentration
0.61 ug/ul in antibody stabilization buffer (lot specific)
Preparation and Storage
-20 degree C for long term storage
Matching Pairs
Antibody: DOC2B (MBS541433)
Positive Control: DOC2B (MBS542710)
Antibody/Peptide Pairs
DOC2B peptide (MBS543595) is used for blocking the activity of DOC2B antibody (MBS541433)
Molecular Weight
45,841 Da
3D Structure
ModBase 3D Structure for P70610
Immunogen
Synthetic peptide taken within amino acid region 400-4130 of human DNPK1 protein.
Expression
Expressed in brain; highly enriched in neurons
Molecular Function
calcium-dependent phospholipid binding;transporter activity
Subcellular Location
Cell membrane, Cytoplasm, Membrane
Applications Tested/Suitable for anti-DOC2B antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-DOC2B antibody
Dot Blot: 1:10,000
ELISA: 1:10,000
Western Blot: 1:500

Other Notes

Small volumes of anti-DOC2B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DOC2B purchase

MBS541433 is an antibody targeting DOC2B. Also known as DOC2B Antibody BIOTIN-Conjugated. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DOC2B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
NCBI Official Full Name
Doc2B
UniProt Protein Name
Double C2-like domain-containing protein beta
UniProt Gene Name
Doc2b
UniProt Synonym Gene Names
Doc2-beta
UniProt Entry Name
DOC2B_RAT

UniProt Comments for DOC2B

Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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